Aceon and Ibu drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aceon (perindopril erbumine) and Ibu (ibuprofen). Common drug interactions include renal failure acute among females and angina pectoris among males.

The phase IV clinical study analyzes what interactions people have when they take Aceon and Ibu. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Aceon?

Aceon has active ingredients of perindopril erbumine. It is often used in high blood pressure. eHealthMe is studying from 1,785 Aceon users. Check the latest studies of Aceon.

What is Ibu?

Ibu has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 246,531 Ibu users. Check the latest studies of Ibu.



On Jul, 26, 2026

17 people who take Aceon and Ibu together, and have interactions are studied.

Aceon and Ibu drug interactions.

What are the common drug interactions of Aceon and Ibu, by gender? *:

female:

  1. Renal failure acute (rapid kidney dysfunction)
  2. Angioedema (rapid swelling of the dermis)
  3. Arthralgia (joint pain)
  4. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  5. Blood potassium decreased
  6. Blood sodium decreased
  7. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  8. Cough
  9. Dehydration (dryness resulting from the removal of water)
  10. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)

male:

  1. Angina pectoris (chest pain due to ischemia of the heart muscle)
  2. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  3. Electrocardiogram st segment depression
  4. Electrocardiogram t wave amplitude increased
  5. Haematocrit decreased
  6. Hypotonia (low muscle tone)
  7. Hypoxia (low oxygen in tissues)
  8. International normalised ratio decreased
  9. Intervertebral disc herniation (spinal disc herniation)
  10. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)

What are the common drug interactions of Aceon and Ibu, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anaemia (lack of blood)
  2. Back injury
  3. Blood glucose increased
  4. Blood potassium increased
  5. Cerebral oedema (swelling of brain)
  6. Coma (state of unconsciousness lasting more than six hours)
  7. Electrocardiogram st segment depression
  8. Electrocardiogram t wave amplitude increased
  9. Hypotonia (low muscle tone)
  10. Hypoxia (low oxygen in tissues)

30-39:

n/a

40-49:

  1. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  2. Cough
  3. Dyspnoea (difficult or laboured respiration)

50-59:

  1. Angina pectoris (chest pain due to ischemia of the heart muscle)
  2. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  3. Blood pressure decreased
  4. Haematocrit decreased
  5. Mouth ulceration (mouth ulcers)
  6. Oedema mouth (swelling of mouth)

60+:

  1. Renal failure acute (rapid kidney dysfunction)
  2. Angioedema (rapid swelling of the dermis)
  3. Hypersensitivity
  4. International normalised ratio decreased
  5. Leukopenia (less number of white blood cells in blood)
  6. Lip swelling
  7. Muscle spasms (muscle contraction)
  8. Nervous system disorder (a general class of medical conditions affecting the nervous system)
  9. Pneumonia pneumococcal (pneumococcal pneumonia is a common but serious infection and inflammation of the lungs)
  10. Pruritus (severe itching of the skin)

What are the existing conditions these people have? *

  1. Muscle Spasms (muscle contraction): 2 people, 11.76%
  2. Agitation (state of anxiety or nervous excitement): 2 people, 11.76%
  3. Type 2 Diabetes: 1 person, 5.88%
  4. Sleep Disorder: 1 person, 5.88%
  5. Pulmonary Thrombosis (scarring in the lungs): 1 person, 5.88%
  6. Nausea And Vomiting: 1 person, 5.88%
  7. Nausea (feeling of having an urge to vomit): 1 person, 5.88%
  8. Joint Pain: 1 person, 5.88%
  9. Indigestion: 1 person, 5.88%
  10. Headache (pain in head): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Aceon and Ibu:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Aceon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ibu:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aceon and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ibu and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on perindopril erbumine and ibuprofen (the active ingredients of Aceon and Ibu, respectively), and Aceon and Ibu (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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