Acetaminophen and codeine phosphate and Acyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acetaminophen and codeine phosphate (acetaminophen; codeine phosphate) and Acyclovir (acyclovir). Common drug interactions include cellulitis among females and acute myeloid leukaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Acetaminophen and codeine phosphate and Acyclovir. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Acetaminophen and codeine phosphate?

Acetaminophen and codeine phosphate has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 3,220 Acetaminophen and codeine phosphate users. Check the latest studies of Acetaminophen and codeine phosphate.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.



On Jul, 13, 2026

18 people who take Acetaminophen and codeine phosphate and Acyclovir together, and have interactions are studied.

Acetaminophen and codeine phosphate and Acyclovir drug interactions.

What are the common drug interactions of Acetaminophen And Codeine Phosphate and Acyclovir, by gender? *:

female:

  1. Cellulitis (infection under the skin)
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Tooth infection
  4. Abdominal pain
  5. Brain injury
  6. Constipation
  7. Nausea (feeling of having an urge to vomit)
  8. Pancreatitis (inflammation of pancreas)
  9. Agitation (state of anxiety or nervous excitement)
  10. Ataxia (loss of full control of bodily movements)

male:

  1. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  2. Renal failure acute (rapid kidney dysfunction)
  3. Melaena (the passage of black, tarry stools)
  4. Oedema peripheral (superficial swelling)
  5. Oesophageal varices haemorrhage (bleeding from extremely dilated sub-mucosal veins in the lower third of the oesophagus)
  6. Pericardial effusion (fluid around the heart)
  7. Portal hypertension (increase in the blood pressure within a system of veins called the portal venous system)
  8. Portal vein thrombosis (venous thrombosis affecting the hepatic portal vein)
  9. Psychiatric symptom
  10. Ascites (accumulation of fluid in the abdominal cavity)

What are the common drug interactions of Acetaminophen And Codeine Phosphate and Acyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Agitation (state of anxiety or nervous excitement)
  2. Ataxia (loss of full control of bodily movements)
  3. Gait disturbance
  4. Irritability

10-19:

n/a

20-29:

n/a

30-39:

  1. Cardiomegaly (increased size of heart than normal)
  2. Cardiomyopathy (weakening of the heart muscle)
  3. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  4. Dyspnoea exertional (breathlessness or shortness of breath)
  5. Electrocardiogram abnormal
  6. Hyperglycaemic hyperosmolar nonketotic syndrome (too much sugar (glucose) in your blood)
  7. Oedema peripheral (superficial swelling)
  8. Pericardial effusion (fluid around the heart)

40-49:

  1. Ascites (accumulation of fluid in the abdominal cavity)
  2. Melaena (the passage of black, tarry stools)
  3. Oesophageal varices haemorrhage (bleeding from extremely dilated sub-mucosal veins in the lower third of the oesophagus)
  4. Portal hypertension (increase in the blood pressure within a system of veins called the portal venous system)
  5. Portal vein thrombosis (venous thrombosis affecting the hepatic portal vein)

50-59:

  1. Abdominal pain
  2. Constipation
  3. Pancreatitis (inflammation of pancreas)

60+:

  1. Cellulitis (infection under the skin)
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Gastritis (inflammation of stomach)
  4. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  5. Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
  6. Parkinson's disease
  7. Pneumonia
  8. Sleep disorder
  9. Syncope (loss of consciousness with an inability to maintain postural tone)
  10. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)

What are the existing conditions these people have? *

  1. Depression: 7 people, 38.89%
  2. Hypercalcaemia (elevated calcium (ca+) level in the blood): 4 people, 22.22%
  3. Constipation: 4 people, 22.22%
  4. High Blood Pressure: 4 people, 22.22%
  5. Herpes Zoster: 3 people, 16.67%
  6. Nausea (feeling of having an urge to vomit): 3 people, 16.67%
  7. Stress And Anxiety: 3 people, 16.67%
  8. Hypotension (abnormally low blood pressure): 2 people, 11.11%
  9. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 11.11%
  10. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Acetaminophen and codeine phosphate and Acyclovir:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acetaminophen and codeine phosphate:

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Browse all side effects of Acyclovir:

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Browse all interactions between Acetaminophen and codeine phosphate and drugs from A to Z:

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Browse all interactions between Acyclovir and drugs from A to Z:

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Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; codeine phosphate and acyclovir (the active ingredients of Acetaminophen and codeine phosphate and Acyclovir, respectively), and Acetaminophen and codeine phosphate and Acyclovir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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