Acetaminophen and codeine phosphate and Hydrocodone bitartrate and acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acetaminophen and codeine phosphate (acetaminophen; codeine phosphate) and Hydrocodone bitartrate and acetaminophen (acetaminophen; hydrocodone bitartrate). Common drug interactions include asthenia among females and cardiac arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Acetaminophen and codeine phosphate and Hydrocodone bitartrate and acetaminophen. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Acetaminophen and codeine phosphate?

Acetaminophen and codeine phosphate has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 3,220 Acetaminophen and codeine phosphate users. Check the latest studies of Acetaminophen and codeine phosphate.

What is Hydrocodone bitartrate and acetaminophen?

Hydrocodone bitartrate and acetaminophen has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 67,662 Hydrocodone bitartrate and acetaminophen users. Check the latest studies of Hydrocodone bitartrate and acetaminophen.



On Jul, 11, 2026

13 people who take Acetaminophen and codeine phosphate and Hydrocodone bitartrate and acetaminophen together, and have interactions are studied.

Acetaminophen and codeine phosphate and Hydrocodone bitartrate and acetaminophen drug interactions.

What are the common drug interactions of Acetaminophen And Codeine Phosphate and Hydrocodone Bitartrate And Acetaminophen, by gender? *:

female:

  1. Asthenia (weakness)
  2. Bradycardia (abnormally slow heart action)
  3. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  4. Hypertension (high blood pressure)
  5. Urinary tract infection
  6. Arthralgia (joint pain)
  7. Cardioactive drug level increased
  8. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  9. Dyspnoea (difficult or laboured respiration)
  10. Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)

male:

  1. Cardiac arrest
  2. Completed suicide (act of taking one's own life)
  3. Coagulopathy (blood's ability to clot is impaired)
  4. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  5. Conjunctival haemorrhage (bleeding underneath the conjunctiva)
  6. Decreased activity
  7. Dyspnoea exertional (breathlessness or shortness of breath)
  8. Dystonia (abnormal muscle tone)
  9. Emotional disorder
  10. Erythema (redness of the skin)

What are the common drug interactions of Acetaminophen And Codeine Phosphate and Hydrocodone Bitartrate And Acetaminophen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Cardiac arrest
  2. Completed suicide (act of taking one's own life)
  3. Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)

30-39:

n/a

40-49:

n/a

50-59:

  1. Hypertension (high blood pressure)
  2. Retching (strong involuntary effort to vomit)
  3. Sinusitis (inflammation of sinus)
  4. Vomiting

60+:

  1. Bradycardia (abnormally slow heart action)
  2. Asthenia (weakness)
  3. Pain in extremity
  4. Chest pain
  5. Multiple injuries
  6. Fatigue (feeling of tiredness)
  7. Haemoglobin decreased
  8. Injury
  9. Oedema peripheral (superficial swelling)
  10. Anaemia (lack of blood)

* Approximation only. Some reports may have incomplete information.

Do you take Acetaminophen and codeine phosphate and Hydrocodone bitartrate and acetaminophen?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Acetaminophen and codeine phosphate and Hydrocodone bitartrate and acetaminophen:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acetaminophen and codeine phosphate:

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Browse all side effects of Hydrocodone bitartrate and acetaminophen:

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Browse all interactions between Acetaminophen and codeine phosphate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydrocodone bitartrate and acetaminophen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; codeine phosphate and acetaminophen; hydrocodone bitartrate (the active ingredients of Acetaminophen and codeine phosphate and Hydrocodone bitartrate and acetaminophen, respectively), and Acetaminophen and codeine phosphate and Hydrocodone bitartrate and acetaminophen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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