Acetaminophen and codeine phosphate and Indapamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acetaminophen and codeine phosphate (acetaminophen; codeine phosphate) and Indapamide (indapamide). Common drug interactions include malaise among females and palmar-plantar erythrodysaesthesia syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Acetaminophen and codeine phosphate and Indapamide. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Acetaminophen and codeine phosphate?

Acetaminophen and codeine phosphate has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 3,220 Acetaminophen and codeine phosphate users. Check the latest studies of Acetaminophen and codeine phosphate.

What is Indapamide?

Indapamide has active ingredients of indapamide. It is often used in high blood pressure. eHealthMe is studying from 22,152 Indapamide users. Check the latest studies of Indapamide.



On Jul, 12, 2026

12 people who take Acetaminophen and codeine phosphate and Indapamide together, and have interactions are studied.

Acetaminophen and codeine phosphate and Indapamide drug interactions.

What are the common drug interactions of Acetaminophen And Codeine Phosphate and Indapamide, by gender? *:

female:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Miosis (constriction of the pupil of the eye, resulting from a normal response to an increase in light)
  3. Psychomotor retardation (motor mental retardation)
  4. Somnolence (a state of near-sleep, a strong desire for sleep)
  5. Aortic valve disease
  6. Mitral valve disease (disease of mitral valve of heart)
  7. Overdose

male:

  1. Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
  2. Asthenia (weakness)
  3. Mucosal inflammation (infection of mucous membrane)
  4. Myalgia (muscle pain)
  5. Nausea (feeling of having an urge to vomit)
  6. Oesophageal haemorrhage (bleeding from oesophagus)
  7. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  8. Pulmonary embolism (blockage of the main artery of the lung)
  9. Pulmonary haemorrhage (acute bleeding from the lung)
  10. Renal failure (kidney dysfunction)

What are the common drug interactions of Acetaminophen And Codeine Phosphate and Indapamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Asthenia (weakness)
  2. Blindness
  3. Bone disorder
  4. Diarrhoea
  5. Dysgeusia (disorder of the sense of taste)
  6. Scotoma (an area of diminished vision within the visual field)
  7. Alopecia (absence of hair from areas of the body)
  8. Aortic valve disease
  9. Deafness neurosensory
  10. Macrocytosis (enlargement of red blood cells with near-constant haemoglobin concentration)

60+:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Miosis (constriction of the pupil of the eye, resulting from a normal response to an increase in light)
  3. Psychomotor retardation (motor mental retardation)
  4. Somnolence (a state of near-sleep, a strong desire for sleep)
  5. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  6. Oesophageal haemorrhage (bleeding from oesophagus)
  7. Overdose
  8. Pulmonary embolism (blockage of the main artery of the lung)
  9. Pulmonary haemorrhage (acute bleeding from the lung)

What are the existing conditions these people have? *

  1. Renal Cell Carcinoma (a kidney cancer): 3 people, 25.00%
  2. Infection Parasitic: 3 people, 25.00%
  3. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 3 people, 25.00%
  4. Hyperglycemia (high blood sugar): 3 people, 25.00%
  5. Diabetes: 3 people, 25.00%
  6. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 2 people, 16.67%
  7. Weight Decreased: 1 person, 8.33%
  8. Gastric Cancer (stomach cancer): 1 person, 8.33%
  9. Back Pain: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Acetaminophen and codeine phosphate and Indapamide:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acetaminophen and codeine phosphate:

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Browse all side effects of Indapamide:

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Browse all interactions between Acetaminophen and codeine phosphate and drugs from A to Z:

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Browse all interactions between Indapamide and drugs from A to Z:

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How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; codeine phosphate and indapamide (the active ingredients of Acetaminophen and codeine phosphate and Indapamide, respectively), and Acetaminophen and codeine phosphate and Indapamide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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