Acetaminophen and codeine phosphate and Topiramate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acetaminophen and codeine phosphate (acetaminophen; codeine phosphate) and Topiramate (topiramate). Common drug interactions include anger among females and rash among males.

The phase IV clinical study analyzes what interactions people have when they take Acetaminophen and codeine phosphate and Topiramate. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Acetaminophen and codeine phosphate?

Acetaminophen and codeine phosphate has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 3,220 Acetaminophen and codeine phosphate users. Check the latest studies of Acetaminophen and codeine phosphate.

What is Topiramate?

Topiramate has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 49,809 Topiramate users. Check the latest studies of Topiramate.

On Jul, 11, 2026

32 people who take Acetaminophen and codeine phosphate and Topiramate together, and have interactions are studied.

Acetaminophen and codeine phosphate and Topiramate drug interactions.

What are the common drug interactions of Acetaminophen And Codeine Phosphate and Topiramate, by gender? *:

female:

Anger
Constipation
Drug toxicity
Memory impairment
Visual impairment
Abnormal behaviour
Acidosis (build-up of carbon dioxide in the blood)
Alanine aminotransferase increased
Anaphylactic reaction (serious allergic reaction)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)

male:

Rash
Furuncle (infection of the hair follicle)
Fall
Hypoaesthesia (reduced sense of touch or sensation)
Loss of consciousness
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Sensation of pressure
Neutropenia (an abnormally low number of neutrophils)

What are the common drug interactions of Acetaminophen And Codeine Phosphate and Topiramate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anger
Constipation
Memory impairment
Visual impairment
Fatigue (feeling of tiredness)

40-49:

Rash
Furuncle (infection of the hair follicle)
Depression
Neutropenia (an abnormally low number of neutrophils)

50-59:

Death
Electrocardiogram qrs complex shortened
Hyperhidrosis (abnormally increased sweating)
Hypotension (abnormally low blood pressure)
Poisoning
Sluggishness (lacking alertness)
Suicide attempt
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tachypnoea (a condition of rapid breathing over 20 per minute)
Unresponsive to stimuli

60+:

Fall
Hypoaesthesia (reduced sense of touch or sensation)
Loss of consciousness
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Sensation of pressure

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 12.50%
Headache (pain in head): 3 people, 9.38%
Depression: 3 people, 9.38%

* Approximation only. Some reports may have incomplete information.

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