Acetaminophen and Evening primrose oil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acetaminophen (acetaminophen) and Evening primrose oil (evening primrose oil). Common drug interactions include nausea among females and urinary tract infection among males.

The phase IV clinical study analyzes what interactions people have when they take Acetaminophen and Evening primrose oil. It is created by eHealthMe based on reports of 74 people who take the same drugs from the FDA, and is updated regularly.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

What is Evening primrose oil?

Evening primrose oil has active ingredients of evening primrose oil. It is often used in premenstrual syndrome. eHealthMe is studying from 1,392 Evening primrose oil users. Check the latest studies of Evening primrose oil.

On Aug, 08, 2026

74 people who take Acetaminophen and Evening primrose oil together, and have interactions are studied.

Acetaminophen and Evening primrose oil drug interactions.

What are the common drug interactions of Acetaminophen and Evening Primrose Oil, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Diarrhoea
Back pain
Fatigue (feeling of tiredness)
Sinusitis (inflammation of sinus)
Arthralgia (joint pain)
Chills (felling of cold)
Vertigo
Vomiting
Nasopharyngitis (inflammation of the nasopharynx)

male:

Urinary tract infection
Polyomavirus test positive
Neutropenia (an abnormally low number of neutrophils)
Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
Pathogen resistance
Quadriplegia (a four limb paralysis)
Septic shock (shock due to blood infection)
Staphylococcal infection (an infection with staphylococcus bacteria)
Thrombocytopenia (decrease of platelets in blood)
Acute myocardial infarction (acute heart attack)

What are the common drug interactions of Acetaminophen and Evening Primrose Oil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Large intestine perforation (hole in large intestine)
Perirectal abscess
Platelet count increased
Pre-eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman)
Premature labour
Procedural hypotension
Procedural nausea
Protein total decreased
Red blood cell count decreased
Wound dehiscence (a surgical incision reopens either internally or externally)

40-49:

Cervical spinal stenosis (narrowing of the spinal canal in the neck)
Optic neuritis (optic nerve inflammation)

50-59:

Nausea (feeling of having an urge to vomit)
Diarrhoea
Fatigue (feeling of tiredness)
Urinary tract infection
Chills (felling of cold)
Back pain
Bacterial infection
Cyst (a closed sac)
Dizziness
Dyspepsia (indigestion)

60+:

Polyomavirus test positive
Urinary tract infection
Hypoacusis (loss of hearing)
Ear discomfort
Acute myocardial infarction (acute heart attack)
Knee arthroplasty
Leukocytosis (increased white blood cells)
Neutropenia (an abnormally low number of neutrophils)
Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
Thrombocytopenia (decrease of platelets in blood)

What are the existing conditions these people have? *

Breast Cancer Metastatic: 34 people, 45.95%
Rashes (redness): 25 people, 33.78%
Stomatitis (inflammation of mucous membrane of mouth): 24 people, 32.43%
Oral Herpes (viral infection of mouth): 24 people, 32.43%
Immunodeficiency Common Variable: 15 people, 20.27%
Immunodeficiency: 5 people, 6.76%
Diarrhea: 5 people, 6.76%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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