Acetaminophen and Lodine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acetaminophen (acetaminophen) and Lodine (etodolac). Common drug interactions include hypertension among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Acetaminophen and Lodine. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

What is Lodine?

Lodine has active ingredients of etodolac. It is often used in pain. eHealthMe is studying from 3,846 Lodine users. Check the latest studies of Lodine.

On Jul, 13, 2026

44 people who take Acetaminophen and Lodine together, and have interactions are studied.

Acetaminophen and Lodine drug interactions.

What are the common drug interactions of Acetaminophen and Lodine, by gender? *:

female:

Hypertension (high blood pressure)
Sinusitis (inflammation of sinus)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Anxiety
Asthenia (weakness)
Asthma
Cholecystitis chronic (long lasting infection of gallbladder)
Chronic kidney disease
Constipation
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

male:

Asthenia (weakness)
Dizziness
Death
Decreased interest
Deformity (disfigurement)
Dry eye (lack of adequate tears)
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Emotional distress
Failure to thrive (inadequate weight gain and physical growth in children)

What are the common drug interactions of Acetaminophen and Lodine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain
Abdominal pain upper
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Constipation
Gallbladder pain
Nausea (feeling of having an urge to vomit)
Portal triaditis
Post procedural complication
Splenomegaly (enlargement of spleen)

30-39:

Abdominal pain
Acute hepatic failure
Alanine aminotransferase increased
Anuria (failure of the kidneys to produce urine)
Aspartate aminotransferase increased
Blood albumin decreased
Blood alkaline phosphatase increased
Blood bilirubin increased
C-reactive protein increased
Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)

40-49:

Pancreatitis (inflammation of pancreas)
Cardiac failure congestive
Chest discomfort
Cough
Drug abuser
Dyspnoea at rest (difficult or laboured breathing during rest)
Dyspnoea exertional (breathlessness or shortness of breath)
Hypertension (high blood pressure)
Ill-defined disorder
Injury

50-59:

Acute sinusitis
Bacteraemia (presence of bacteria in the blood)
Catheter site infection (infection at the site of insertion)
Dysphagia (a condition in which swallowing is difficult or painful)
Hepatitis (inflammation of the liver)
Hepatocellular damage (liver damage)
Hypersensitivity
Injection site erythema (redness at injection site)
Injection site pain
Injection site swelling

60+:

Asthenia (weakness)
Dizziness
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Somnolence (a state of near-sleep, a strong desire for sleep)
Spinal osteoarthritis (joint cartilage loss in spine)
Thrombocytopenia (decrease of platelets in blood)
Tricuspid valve incompetence (inefficient heart valve)
Weight decreased
Abdominal pain upper
Anaemia (lack of blood)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 15.91%
High Blood Pressure: 5 people, 11.36%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 9.09%
Multiple Myeloma (cancer of the plasma cells): 3 people, 6.82%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.82%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

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