Actemra and Euthyrox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Actemra (tocilizumab) and Euthyrox (levothyroxine sodium). Common drug interactions include pain among females and agranulocytosis among males.

The phase IV clinical study analyzes what interactions people have when they take Actemra and Euthyrox. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Actemra?

Actemra has active ingredients of tocilizumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 102,759 Actemra users. Check the latest studies of Actemra.

What is Euthyrox?

Euthyrox has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 8,740 Euthyrox users. Check the latest studies of Euthyrox.

On Jul, 14, 2026

14 people who take Actemra and Euthyrox together, and have interactions are studied.

What are the common drug interactions of Actemra and Euthyrox, by gender? *:

female:

Pain
Drug ineffective
Pain in extremity
Blood pressure increased
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Food allergy
Hallucination (an experience involving the perception of something not present)
Headache (pain in head)
Incontinence (lack of moderation or self-control)

male:

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Leukopenia (less number of white blood cells in blood)
Arthropathy
Cellulitis (infection under the skin)
Infection
Pain
Pyrexia (fever)
Swelling

What are the common drug interactions of Actemra and Euthyrox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Escherichia urinary tract infection (urinary tract infection by escherichia coli)
Maternal exposure during pregnancy (use of substance during pregnancy)
Urinary tract infection enterococcal

40-49:

C-reactive protein increased
Urinary tract infection

50-59:

Arthralgia (joint pain)
Nausea (feeling of having an urge to vomit)
Incontinence (lack of moderation or self-control)
Urinary tract inflammation
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Leukopenia (less number of white blood cells in blood)
Abdominal distension
Abdominal pain upper
Alopecia (absence of hair from areas of the body)
Arterial disorder

60+:

n/a

What are the existing conditions these people have? *

Upper Gastrointestinal Haemorrhage (upper gastrointestinal bleeding): 3 people, 21.43%
High Blood Pressure: 3 people, 21.43%
Pain: 2 people, 14.29%
Lung Adenocarcinoma (a form of non-small cell lung cancer): 2 people, 14.29%
Embolism Venous (embolus may pass into the arterial system): 2 people, 14.29%
Type 2 Diabetes: 1 person, 7.14%
Thyroid Diseases: 1 person, 7.14%
Thrombosis (formation of a blood clot inside a blood vessel): 1 person, 7.14%
Takayasu's Arteritis (an inflammation of the aorta -- the artery that carries blood from the heart to the rest of the body): 1 person, 7.14%
Joint Pain: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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