Acth and Xarelto drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acth (corticotropin) and Xarelto (rivaroxaban). Common drug interactions include infusion site swelling among females and blood pressure increased among males.

The phase IV clinical study analyzes what interactions people have when they take Acth and Xarelto. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Acth?

Acth has active ingredients of corticotropin. eHealthMe is studying from 5,402 Acth users. Check the latest studies of Acth.

What is Xarelto?

Xarelto has active ingredients of rivaroxaban. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 212,377 Xarelto users. Check the latest studies of Xarelto.

On Jul, 26, 2026

37 people who take Acth and Xarelto together, and have interactions are studied.

What are the common drug interactions of Acth and Xarelto, by gender? *:

female:

Infusion site swelling
Klebsiella infection
Limb discomfort (discomfort in leg)
Lip swelling
Post procedural complication
Pouchitis (inflammatory bowel disease)
Red blood cell sedimentation rate increased
Snoring
Swelling face
Swollen tongue (swelling of tongue)

male:

Blood pressure increased
Chest discomfort
Cushingoid (obesity and weakening of the muscles)
Depressed mood
Fall
Hypertension (high blood pressure)
Hypoacusis (loss of hearing)
Muscle spasms (muscle contraction)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pain

What are the common drug interactions of Acth and Xarelto, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Dizziness
Ear discomfort
Fatigue (feeling of tiredness)
Limb discomfort (discomfort in leg)
Red blood cell sedimentation rate increased
Snoring
Swelling face
Vision blurred

40-49:

Pneumonia
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pulmonary embolism (blockage of the main artery of the lung)

50-59:

n/a

60+:

Erythema (redness of the skin)
Dizziness
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
Injection site bruising
Injection site discolouration
Injection site pain
Injection site paraesthesia (abnormal skin sensations at injection site)
Injection site pruritus (severe itching at injection site)
Injection site warmth
Malaise (a feeling of general discomfort or uneasiness)

What are the existing conditions these people have? *

Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 9 people, 24.32%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 6 people, 16.22%
Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 4 people, 10.81%
Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 4 people, 10.81%
Sympathetic Ophthalmia (inflammatory condition affecting both eyes that occurs after a penetrating injury): 3 people, 8.11%
Immunodeficiency Common Variable: 3 people, 8.11%
Vasculitis (inflammation of a blood vessel or blood vessels): 2 people, 5.41%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 5.41%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 5.41%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

Do you take Acth and Xarelto?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously