Acth and Zonegran drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acth (corticotropin) and Zonegran (zonisamide). Common drug interactions include convulsion among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Acth and Zonegran. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Acth?

Acth has active ingredients of corticotropin. eHealthMe is studying from 5,402 Acth users. Check the latest studies of Acth.

What is Zonegran?

Zonegran has active ingredients of zonisamide. It is often used in epilepsy. eHealthMe is studying from 6,211 Zonegran users. Check the latest studies of Zonegran.

On Aug, 09, 2026

20 people who take Acth and Zonegran together, and have interactions are studied.

What are the common drug interactions of Acth and Zonegran, by gender? *:

female:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Irritability
Abnormal behaviour
Cardiomyopathy (weakening of the heart muscle)
Drug ineffective
Pneumocystis jiroveci pneumonia (fungal infection of the lungs)
Pneumonia streptococcal (pneumonia, caused by streptococcus pneumoniae)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Somnolence (a state of near-sleep, a strong desire for sleep)
Asthenia (weakness)

male:

Drug ineffective
Lethargy (tiredness)
Conjunctival oedema (conjunctival swelling)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Glaucoma (increased fluid pressure in the eye with vision loss)
Open angle glaucoma (an eye disease that gradually steals vision)
Papilloedema (optic disc swelling)
Red eye
Weight increased
Drug effect decreased

What are the common drug interactions of Acth and Zonegran, by age (0-1 to 60+)? *:

0-1:

Cardiomyopathy (weakening of the heart muscle)
Pneumocystis jiroveci pneumonia (fungal infection of the lungs)
Haematochezia (passage of stools containing blood)
Haematuria (presence of blood in urine)
Hemiparesis (weakness on one side of the body)
Hypertension (high blood pressure)
Irritability
Lacrimation increased
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Muscle spasms (muscle contraction)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Infantile Spasms: 14 people, 70.00%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 10.00%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 10.00%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 5.00%
Pain: 1 person, 5.00%
Nausea And Vomiting: 1 person, 5.00%
Fever: 1 person, 5.00%
Constipation: 1 person, 5.00%
Complex Partial Seizures (epileptic seizure): 1 person, 5.00%
Bowel Movement Irregularity: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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