Actigall and Lexapro drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Actigall (ursodiol) and Lexapro (escitalopram oxalate). Common drug interactions include decreased appetite among females and fall among males.
The phase IV clinical study analyzes what interactions people have when they take Actigall and Lexapro. It is created by eHealthMe based on reports of 97 people who take the same drugs from the FDA, and is updated regularly.
What is Actigall?
Actigall has active ingredients of ursodiol. It is often used in gallstones. eHealthMe is studying from 2,162 Actigall users. Check the latest studies of Actigall.
What is Lexapro?
Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.
97 people who take Actigall and Lexapro together, and have interactions are studied.

What are the common drug interactions of Actigall and Lexapro, by gender? *:
female:
- Decreased appetite
- Fatigue (feeling of tiredness)
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Respiratory syncytial virus infection (viral disease of respiratory system)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Vomiting
- Cellulitis (infection under the skin)
- Cough
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
male:
- Fall
- Pain
- Anaemia (lack of blood)
- Hyperglycaemia (high blood sugar)
- Asthenia (weakness)
- Blood creatinine increased
- Hypertension (high blood pressure)
- Pneumonia
- Blood urea increased
- Dyspnoea (difficult or laboured respiration)
What are the common drug interactions of Actigall and Lexapro, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Agitation (state of anxiety or nervous excitement)
- Anaemia (lack of blood)
- Aspartate aminotransferase increased
- Blood bilirubin increased
- Decreased appetite
- Febrile neutropenia (fever with reduced white blood cells)
- Hypokalaemia (low potassium)
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Hypotension (abnormally low blood pressure)
20-29:
- Pneumonia
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Vomiting
- Abdominal pain
- Anaemia (lack of blood)
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
- Constipation
- Diarrhoea
- Electrocardiogram qt prolonged
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
30-39:
- Acidosis (build-up of carbon dioxide in the blood)
- Acute respiratory distress syndrome
- Anaemia (lack of blood)
- Asthenia (weakness)
- Bandaemia (excess of band cells (immature white blood cells) released by the bone marrow into the blood)
- Blood creatinine increased
- Blood urea increased
- Bronchial haemorrhage (bleeding in bronchia)
- Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
- Constipation
40-49:
- Hyperglycaemia (high blood sugar)
- Pancreatitis acute (sudden inflammation of pancreas)
- Back pain
- Blood pressure increased
- Disease progression
- Glioblastoma multiforme (most common and deadliest of malignant primary brain tumours in adults)
- Hypertension (high blood pressure)
- Abdominal pain
- Abdominal pain upper
- Anaemia (lack of blood)
50-59:
- Renal injury (kidney injury)
- Colon cancer
- Cough
- Increased upper airway secretion
- Local swelling (swelling at the site of some application of substance or injury)
- Oropharyngeal pain
- White blood cell count decreased
- Nausea (feeling of having an urge to vomit)
- Erythema (redness of the skin)
- Memory impairment
60+:
- Pneumonia
- Dyspnoea (difficult or laboured respiration)
- Joint dislocation (a joint position is changed from normal position)
- Joint effusion (presence of extra fluid in joint covering)
- Lower limb fracture
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Osteoporosis (bones weak and more likely to break)
- Pain
- Peripheral swelling
- Acute respiratory distress syndrome
What are the existing conditions these people have? *
- Nausea (feeling of having an urge to vomit): 27 people, 27.84%
- Pain: 24 people, 24.74%
- Cough: 15 people, 15.46%
- High Blood Pressure: 14 people, 14.43%
- Agitation (state of anxiety or nervous excitement): 12 people, 12.37%
- Sleep Disorder: 12 people, 12.37%
- Cystic Fibrosis (disease of the secretary glands): 12 people, 12.37%
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 11 people, 11.34%
- Wheezing (a high-pitched whistling sound made while you breath): 11 people, 11.34%
- Sedation: 11 people, 11.34%
* Approximation only. Some reports may have incomplete information.
Do you take Actigall and Lexapro?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Actigall and Lexapro:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Actigall:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lexapro:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Actigall and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lexapro and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on ursodiol and escitalopram oxalate (the active ingredients of Actigall and Lexapro, respectively), and Actigall and Lexapro (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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