Activase and Valacyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Activase (alteplase) and Valacyclovir (valacyclovir hydrochloride). Common drug interactions include alanine aminotransferase increased among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Activase and Valacyclovir. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Activase?

Activase has active ingredients of alteplase. eHealthMe is studying from 7,526 Activase users. Check the latest studies of Activase.

What is Valacyclovir?

Valacyclovir has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 42,107 Valacyclovir users. Check the latest studies of Valacyclovir.

On Jul, 16, 2026

12 people who take Activase and Valacyclovir together, and have interactions are studied.

Activase and Valacyclovir drug interactions.

What are the common drug interactions of Activase and Valacyclovir, by gender? *:

female:

Alanine aminotransferase increased
Anxiety
Aortic arteriosclerosis (hardening of the aortic arteries)
Ascites (accumulation of fluid in the abdominal cavity)
Bone disorder
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Breast cancer metastatic
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Constipation

male:

Anaemia (lack of blood)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Febrile neutropenia (fever with reduced white blood cells)
Fungal infection
Haematocrit decreased
Haemoglobin decreased
Hyperbilirubinaemia (excess of bilirubin in the blood)
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
Hyperuricaemia (level of uric acid in the blood that is abnormally high)

What are the common drug interactions of Activase and Valacyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Caecitis (inflammation of the cecum)
Chemical eye injury
Collapse of lung (functional breakdown of lung)
Corneal abrasion (loss of the surface of cornea)
Epistaxis (bleed from the nose)
Fatigue (feeling of tiredness)
Febrile neutropenia (fever with reduced white blood cells)
Fungal infection
Haematocrit decreased
Haemoglobin decreased

20-29:

n/a

30-39:

n/a

40-49:

Acute respiratory distress syndrome
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Hyperbilirubinaemia (excess of bilirubin in the blood)
Neutropenic colitis (inflammation of the cecum, often with involvement of the ascending colon and ileum, a life threatening condition)
Sepsis (a severe blood infection that can lead to organ failure and death)

50-59:

Pneumonia
White blood cell count decreased

60+:

Alanine aminotransferase increased
Anxiety
Death
Decreased interest
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Deformity (disfigurement)
Discomfort
Dizziness
Dysgeusia (disorder of the sense of taste)
Dyspepsia (indigestion)

What are the existing conditions these people have? *

Stress And Anxiety: 3 people, 25.00%
Reflux Gastritis (a condition in which the lining of a person's stomach becomes inflamed as a result of exposure to bile): 3 people, 25.00%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 25.00%
Pain: 3 people, 25.00%
Breast Cancer: 3 people, 25.00%
Wound Infection Pseudomonas: 1 person, 8.33%
Gingival Pain (gum pain): 1 person, 8.33%
Cellulitis (infection under the skin): 1 person, 8.33%
Chest Pain: 1 person, 8.33%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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