Actrapid and Solu-cortef drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Actrapid (insulin) and Solu-cortef (hydrocortisone sodium succinate). Common drug interactions include drug chemical incompatibility among females and coma among males.

The phase IV clinical study analyzes what interactions people have when they take Actrapid and Solu-cortef. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Actrapid?

Actrapid has active ingredients of insulin. eHealthMe is studying from 4,864 Actrapid users. Check the latest studies of Actrapid.

What is Solu-cortef?

Solu-cortef has active ingredients of hydrocortisone sodium succinate. eHealthMe is studying from 7,983 Solu-cortef users. Check the latest studies of Solu-cortef.

On Jul, 26, 2026

31 people who take Actrapid and Solu-cortef together, and have interactions are studied.

Actrapid and Solu-cortef drug interactions.

What are the common drug interactions of Actrapid and Solu-Cortef, by gender? *:

female:

Drug chemical incompatibility
Blood creatinine increased
Enterobacter infection (infection caused by bacteria of the family enterobacteriaceae)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Oesophageal candidiasis (fungal infection of oesophagus)
Perinephric collection (fluid collections surrounding a kidney)
Pulmonary embolism (blockage of the main artery of the lung)
Renal transplant
Torsade de pointes (a abnormal heart rate with abnormal beating pattern)

male:

Coma (state of unconsciousness lasting more than six hours)
Drug effect prolonged
Brain injury
Dilatation ventricular
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Electrocardiogram t wave inversion
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Pulmonary arterial pressure increased
Syncope (loss of consciousness with an inability to maintain postural tone)

What are the common drug interactions of Actrapid and Solu-Cortef, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anastomotic leak
Hyperkalaemia (damage to or disease of the kidney)
Intra-abdominal haemorrhage (intra-abdominal bleeding)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Renal failure (kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)
Thrombocytopenia (decrease of platelets in blood)

30-39:

Drug chemical incompatibility

40-49:

n/a

50-59:

Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Torsade de pointes (a abnormal heart rate with abnormal beating pattern)
Ventricular fibrillation (abnormally irregular heart rhythm)
Acute myocardial infarction (acute heart attack)

60+:

Coma (state of unconsciousness lasting more than six hours)
Drug effect prolonged
Pulmonary embolism (blockage of the main artery of the lung)
Renal transplant
Urinary tract infection
Wound dehiscence (a surgical incision reopens either internally or externally)
Wound secretion
Asthma
Cardiac arrest
Depressed level of consciousness

What are the existing conditions these people have? *

Infection: 14 people, 45.16%
Sedation: 11 people, 35.48%
Asthma: 8 people, 25.81%
Hyperglycemia (high blood sugar): 7 people, 22.58%
Blood Glucose Abnormal: 7 people, 22.58%
Hypersensitivity: 7 people, 22.58%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 7 people, 22.58%
Metabolic Alkalosis (too much bicarbonate in the blood): 7 people, 22.58%
Fungal Infection: 7 people, 22.58%
Reversal Of Sedation: 7 people, 22.58%

* Approximation only. Some reports may have incomplete information.

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