Acular and Cipro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acular (ketorolac tromethamine) and Cipro (ciprofloxacin hydrochloride). Common drug interactions include bunion among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Acular and Cipro. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Acular?

Acular has active ingredients of ketorolac tromethamine. eHealthMe is studying from 1,125 Acular users. Check the latest studies of Acular.

What is Cipro?

Cipro has active ingredients of ciprofloxacin hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 35,126 Cipro users. Check the latest studies of Cipro.

On Jul, 17, 2026

33 people who take Acular and Cipro together, and have interactions are studied.

What are the common drug interactions of Acular and Cipro, by gender? *:

female:

Bunion (a painful swelling on the first joint of the big toe)
Chronic kidney disease
Dementia (madness)
Duodenal ulcer
Dyspnoea (difficult or laboured respiration)
Gait disturbance
Osteonecrosis (death of bone)
Spinal compression fracture (fracture due to spinal compression on bone)
Anxiety
Bone callus excessive (excessive bony deposit formed between and around the broken ends of bone fractures)

male:

Cardiac failure congestive
International normalised ratio increased
Cardiomyopathy (weakening of the heart muscle)
Cholecystitis (infection of gallbladder)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Depression
Dizziness
Dyspnoea (difficult or laboured respiration)
Flatulence (flatus expelled through the anus)
Fluid overload (too much fluid in the blood)

What are the common drug interactions of Acular and Cipro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abnormal weight gain
Adverse reaction
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Cataract (clouding of the lens inside the eye)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Contusion (a type of hematoma of tissue in which capillaries)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Device expulsion
Drug intolerance (drug sensitivity)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Dizziness
Dyspnoea (difficult or laboured respiration)
Flatulence (flatus expelled through the anus)
Fluid overload (too much fluid in the blood)
Hepatosplenomegaly (enlargement of both the liver and the spleen)
Hypertension (high blood pressure)
Hypertensive heart disease
International normalised ratio increased
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Palpitations (feelings or sensations that your heart is pounding or racing)

60+:

Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Fall
Multiple injuries
Osteonecrosis (death of bone)
Pain in extremity
Spinal compression fracture (fracture due to spinal compression on bone)
Surgery
Unresponsive to stimuli
Anaemia (lack of blood)
Blood glucose increased

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 30.30%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 30.30%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 12.12%
Osteoporosis (bones weak and more likely to break): 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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