Diprolene and Simvastatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diprolene (betamethasone dipropionate) and Simvastatin (simvastatin). Common drug interactions include psoriasis among females and decreased appetite among males.

The phase IV clinical study analyzes what interactions people have when they take Diprolene and Simvastatin. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Diprolene?

Diprolene has active ingredients of betamethasone dipropionate. eHealthMe is studying from 1,048 Diprolene users. Check the latest studies of Diprolene.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,969 Simvastatin users. Check the latest studies of Simvastatin.



On Jul, 17, 2026

20 people who take Diprolene and Simvastatin together, and have interactions are studied.

Diprolene and Simvastatin drug interactions.

What are the common drug interactions of Diprolene and Simvastatin, by gender? *:

female:

  1. Psoriasis (immune-mediated disease that affects the skin)
  2. Depression
  3. Disease progression
  4. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  5. Dizziness
  6. Dry skin
  7. Fatigue (feeling of tiredness)
  8. Foot fracture
  9. Herpes zoster
  10. Malaise (a feeling of general discomfort or uneasiness)

male:

  1. Decreased appetite
  2. Diarrhoea
  3. Lethargy (tiredness)
  4. Muscle spasms (muscle contraction)
  5. Myalgia (muscle pain)
  6. Pain in extremity
  7. Somnolence (a state of near-sleep, a strong desire for sleep)
  8. Temperature intolerance (inability to go in temperature)
  9. Acute hepatic failure
  10. Anxiety

What are the common drug interactions of Diprolene and Simvastatin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Psoriasis (immune-mediated disease that affects the skin)

50-59:

  1. Disease progression
  2. Dry skin
  3. Fatigue (feeling of tiredness)
  4. Foot fracture
  5. Parathyroid disorder
  6. Rash
  7. Skin fissures (a crack in the skin)
  8. Skin haemorrhage (bleeding into skin)
  9. Thyroid cyst
  10. Thyroid operation

60+:

  1. Decreased appetite
  2. Diarrhoea
  3. Myalgia (muscle pain)
  4. Pain in extremity
  5. Somnolence (a state of near-sleep, a strong desire for sleep)
  6. Temperature intolerance (inability to go in temperature)
  7. Acute hepatic failure
  8. Anxiety
  9. Application site erythema (redness of the skin at application site)
  10. Application site pruritus (application site severe itching of the skin)

What are the existing conditions these people have? *

  1. Psoriasis (immune-mediated disease that affects the skin): 6 people, 30.00%
  2. Itching: 3 people, 15.00%
  3. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 10.00%
  4. Breast Cancer: 2 people, 10.00%
  5. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 10.00%
  6. Cardiac Disorder: 2 people, 10.00%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 10.00%
  8. Hypersensitivity: 2 people, 10.00%
  9. Heart Valve Incompetence (heart's valves do not work correctly): 1 person, 5.00%
  10. Breast Cancer Female: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Diprolene and Simvastatin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Diprolene and Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Diprolene:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Diprolene and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Simvastatin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on betamethasone dipropionate and simvastatin (the active ingredients of Diprolene and Simvastatin, respectively), and Diprolene and Simvastatin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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