Adalat cc and Tagamet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adalat cc (nifedipine) and Tagamet (cimetidine). Common drug interactions include anaemia among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Adalat cc and Tagamet. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Adalat cc?

Adalat cc has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 5,019 Adalat cc users. Check the latest studies of Adalat cc.

What is Tagamet?

Tagamet has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 9,011 Tagamet users. Check the latest studies of Tagamet.



On Jul, 16, 2026

26 people who take Adalat cc and Tagamet together, and have interactions are studied.

Adalat cc and Tagamet drug interactions.

What are the common drug interactions of Adalat Cc and Tagamet, by gender? *:

female:

  1. Anaemia (lack of blood)
  2. Confusional state
  3. Disseminated intravascular coagulation (systemic activation of blood coagulation)
  4. Drug effect decreased
  5. Drug eruption (adverse drug reaction of the skin)
  6. Electrocardiogram t wave amplitude decreased
  7. Haematemesis (vomiting of blood)
  8. Haematocrit decreased
  9. Haemoglobin decreased
  10. Hypoglycaemic coma (coma due to deficiency of glucose in the bloodstream)

male:

  1. Diarrhoea
  2. Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
  3. Liver abscess (pus in liver)
  4. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  5. Death
  6. Abdominal pain upper
  7. Dyspnoea (difficult or laboured respiration)
  8. Malignant neoplasm progression (cancer tumour came back)
  9. Muscle rigidity (muscle stiffness)
  10. Pain

What are the common drug interactions of Adalat Cc and Tagamet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Diarrhoea
  2. Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
  3. Alopecia (absence of hair from areas of the body)
  4. Ammonia increased
  5. Ileal perforation
  6. Immunosuppressant drug level increased
  7. Death
  8. Abdominal pain upper
  9. Drug effect decreased
  10. Duodenal ulcer haemorrhage (bleeding duodenal ulcer)

60+:

  1. Proteinuria (presence of protein in the urine)
  2. Haemorrhage subcutaneous (bleeding from skin)
  3. Sepsis (a severe blood infection that can lead to organ failure and death)
  4. Abdominal pain upper
  5. Anaemia (lack of blood)
  6. Anxiety
  7. Aortic calcification (aortic calcification sign of heart valve disease)
  8. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
  9. Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
  10. Colitis ulcerative (inflammation of colon with ulcer)

What are the existing conditions these people have? *

  1. Hepatic Neoplasm Malignant (liver cancer): 5 people, 19.23%
  2. Renal Cell Carcinoma Stage Ii (the tumour is larger than 7 centimetres and is found only in the kidney): 4 people, 15.38%
  3. Renal Cell Carcinoma (a kidney cancer): 3 people, 11.54%
  4. Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 3 people, 11.54%
  5. Gastritis (inflammation of stomach): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Adalat cc and Tagamet?

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- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Adalat cc and Tagamet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Adalat cc:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tagamet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adalat cc and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tagamet and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on nifedipine and cimetidine (the active ingredients of Adalat cc and Tagamet, respectively), and Adalat cc and Tagamet (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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