Adcirca and Cubicin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adcirca (tadalafil) and Cubicin (daptomycin). Common drug interactions include diarrhoea among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Adcirca and Cubicin. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Adcirca?

Adcirca has active ingredients of tadalafil. It is often used in pulmonary hypertension. eHealthMe is studying from 54,957 Adcirca users. Check the latest studies of Adcirca.

What is Cubicin?

Cubicin has active ingredients of daptomycin. It is often used in infection. eHealthMe is studying from 7,991 Cubicin users. Check the latest studies of Cubicin.

On Jul, 15, 2026

11 people who take Adcirca and Cubicin together, and have interactions are studied.

What are the common drug interactions of Adcirca and Cubicin, by gender? *:

female:

Diarrhoea
Urinary tract infection
Anaemia (lack of blood)
Back injury
Fall
Hip fracture
Joint swelling
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Sepsis (a severe blood infection that can lead to organ failure and death)
Kidney infection

male:

Anaemia (lack of blood)
Device related infection
Drug hypersensitivity
Eosinophilic pneumonia (eosinophil accumulates in the lung)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Headache (pain in head)
Pneumonia
Pyrexia (fever)
Right ventricular failure (right half of the heart fails to work)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)

What are the common drug interactions of Adcirca and Cubicin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)

50-59:

n/a

60+:

Anaemia (lack of blood)
Back injury
Diarrhoea
Fall
Hip fracture
Joint swelling
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 7 people, 63.64%
Immunodeficiency Common Variable: 3 people, 27.27%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 3 people, 27.27%
Wound Infection Staphylococcal: 1 person, 9.09%
Right Ventricular Failure (right half of the heart fails to work): 1 person, 9.09%
Pneumonia: 1 person, 9.09%
Device Related Infection: 1 person, 9.09%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 1 person, 9.09%
Coughing Up Blood: 1 person, 9.09%
Autoimmune Disorder (a condition in which the immune system attacks the body's normal substances and tissue): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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