Abilify and Aggrenox drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Abilify (aripiprazole) and Aggrenox (aspirin; dipyridamole). Common drug interactions include death among females and upper gastrointestinal haemorrhage among males.
The phase IV clinical study analyzes what interactions people have when they take Abilify and Aggrenox. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.
What is Abilify?
Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,454 Abilify users. Check the latest studies of Abilify.
What is Aggrenox?
Aggrenox has active ingredients of aspirin; dipyridamole. It is often used in stroke. eHealthMe is studying from 7,654 Aggrenox users. Check the latest studies of Aggrenox.
43 people who take Abilify and Aggrenox together, and have interactions are studied.

What are the common drug interactions of Abilify and Aggrenox, by gender? *:
female:
- Death
- Intussusception
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Chronic kidney disease
- Constipation
- Cough
- Dehydration (dryness resulting from the removal of water)
- Dry eye (lack of adequate tears)
- Eyelid margin crusting (crusting at the lid margins, generally worse on waking)
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
male:
- Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
- Abnormal dreams
- Ileus (a painful obstruction of the ileum or other part of the intestine)
- Overdose
- Pain
- Psoriasis (immune-mediated disease that affects the skin)
- Psychotic disorder
- Thirst
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Tremor (trembling or shaking movements in one or more parts of your body)
What are the common drug interactions of Abilify and Aggrenox, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Hepatic enzyme increased
- Chronic kidney disease
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Restlessness (not able to rest)
- Therapeutic response decreased (less preventive response)
50-59:
- Blood pressure increased
- Cholecystitis acute (rapid infection of gallbladder)
- Death
- Diabetic coma
- Overdose
- Sepsis syndrome (a clinical condition of blood infection)
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Urinary tract infection
60+:
- Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Hypovolaemic shock (shock caused by severe blood or fluid loss)
- Intestinal resection
- Intracranial aneurysm (bulging, weak area in the wall of a cranial artery)
- Intussusception
- Ocular hyperaemia (an abnormally large amount of blood in eye)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Polyuria (production of too much dilute urine)
- Pyelonephritis (inflammation of kidney caused by bacteria)
What are the existing conditions these people have? *
- High Blood Pressure: 16 people, 37.21%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 14 people, 32.56%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 32.56%
- Back Pain: 13 people, 30.23%
- Anaemia (lack of blood): 12 people, 27.91%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 12 people, 27.91%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 12 people, 27.91%
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 12 people, 27.91%
- Laryngitis (inflammation of the larynx): 12 people, 27.91%
- Joint Pain: 12 people, 27.91%
* Approximation only. Some reports may have incomplete information.
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Abilify and Aggrenox:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Abilify:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Aggrenox:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Abilify and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Aggrenox and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Cetin, M., Celik, M., Cakici, M., Polat, M., & Suner, A, "Aripiprazole-Induced Hoarseness", Turk Psikiyatri Dergisi, 2018 Jan .
- Cetin M, Celik M, Cakici M, Polat M, Suner A, "Aripiprazole induced non-cardiogenic pulmonary edema: a case report", Turk Psikiyatri Dergisi, 2014 Dec .
- Cetin, M., Celik, M., Cakici, M., Polat, M., & Suner, A, "Aripiprazole-Induced Hoarseness", Turk Psikiyatri Dergisi, 2018 Jan .
- Cetin M, Celik M, Cakici M, Polat M, Suner A, "Aripiprazole induced non-cardiogenic pulmonary edema: a case report", Turk Psikiyatri Dergisi, 2014 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on aripiprazole and aspirin; dipyridamole (the active ingredients of Abilify and Aggrenox, respectively), and Abilify and Aggrenox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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