Paracetamol and Capillary fragility - a phase IV clinical study of FDA data

Summary:

Capillary fragility is reported as a side effect among people who take Paracetamol (acetaminophen), especially for people who are male, 60+ old, also take Gliclazide, and have Essential thrombocythaemia.

The phase IV clinical study analyzes which people have Capillary fragility when taking Paracetamol. It is created by eHealthMe based on reports of 114,713 people who have side effects when taking Paracetamol from the FDA, and is updated regularly.

What is Paracetamol?

Paracetamol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 115,650 Paracetamol users. Check the latest studies of Paracetamol.

What is Capillary fragility?

Capillary fragility (lack in resistance of capillary) is found to be associated with 95 drugs and 243 conditions by eHealthMe. Check the latest studies of Capillary fragility.

On Jul, 15, 2026

114,713 people reported to have side effects when taking Paracetamol.
Among them, 16 people (0.01%) have Capillary fragility.

Could Paracetamol cause Capillary fragility?

Among these 16 people:

What is the gender of people who have Capillary fragility when taking Paracetamol? *

female: 6.67 %
male: 93.33 %

What is the age of people who have Capillary fragility when taking Paracetamol? *

What are other drugs people take besides Paracetamol? *

Zopiclone: 15 people, 93.75%
Movicol: 15 people, 93.75%
Hydrea: 15 people, 93.75%
Gliclazide: 15 people, 93.75%
Clopidogrel: 7 people, 43.75%
Tapentadol Hydrochloride: 1 person, 6.25%
Maxidex: 1 person, 6.25%
Codeine: 1 person, 6.25%

What are other side effects people have besides Capillary fragility? *

Skin Ulcer: 15 people, 93.75%
Rash Erythematous (redness of the skin): 15 people, 93.75%
Amyotrophy (muscular wasting or atrophy): 15 people, 93.75%
Actinic Keratosis (skin disease due to sun exposure): 15 people, 93.75%
Squamous Cell Carcinoma Of Skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin): 5 people, 31.25%
General Physical Health Deterioration (weak health status): 2 people, 12.50%
Peripheral Swelling: 1 person, 6.25%
Nausea (feeling of having an urge to vomit): 1 person, 6.25%
Head Injury: 1 person, 6.25%
Dizziness: 1 person, 6.25%

What are the existing conditions these people have? *

Essential Thrombocythaemia (chronic blood cancer): 14 people, 87.50%
General Physical Health Deterioration (weak health status): 13 people, 81.25%
Inflammation: 10 people, 62.50%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Paracetamol and have Capillary fragility?

- Check whether Capillary fragility is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Paracetamol:

Paracetamol (115,650 reports)

Browse all side effects of Paracetamol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Capillary fragility:

Capillary fragility (95 drugs)

Browse all the conditions that are associated with Capillary fragility:

Capillary fragility (243 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Paracetamol) and Paracetamol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.