Adderall 10 and Excedrin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adderall 10 (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) and Excedrin (acetaminophen; aspirin; caffeine). Common drug interactions include tremor among females and drug hypersensitivity among males.

The phase IV clinical study analyzes what interactions people have when they take Adderall 10 and Excedrin. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Adderall 10?

Adderall 10 has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 5,182 Adderall 10 users. Check the latest studies of Adderall 10.

What is Excedrin?

Excedrin has active ingredients of acetaminophen; aspirin; caffeine. It is often used in headache. eHealthMe is studying from 22,740 Excedrin users. Check the latest studies of Excedrin.



On Jul, 08, 2026

15 people who take Adderall 10 and Excedrin together, and have interactions are studied.

Adderall 10 and Excedrin drug interactions.

What are the common drug interactions of Adderall 10 and Excedrin, by gender? *:

female:

  1. Tremor (trembling or shaking movements in one or more parts of your body)
  2. Abdominal discomfort
  3. Gallbladder disorder
  4. Bipolar disorder (mood disorder)
  5. Drug toxicity
  6. Dyskinesia (abnormality or impairment of voluntary movement)
  7. Haematocrit decreased
  8. Polysubstance dependence
  9. Substance abuse
  10. Abdominal pain upper

male:

  1. Drug hypersensitivity
  2. Abdominal pain upper
  3. Back pain
  4. Palpitations (feelings or sensations that your heart is pounding or racing)
  5. Urinary retention (the inability to completely or partially empty the bladder)

What are the common drug interactions of Adderall 10 and Excedrin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
  2. Difficulty in walking
  3. Dyskinesia (abnormality or impairment of voluntary movement)
  4. Dyspnoea (difficult or laboured respiration)
  5. Fall
  6. Grunting (abnormal, short, deep, hoarse sounds in exhalation that often accompany severe chest pain)
  7. Head injury
  8. Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
  9. Muscle rigidity (muscle stiffness)
  10. Renal pain (kidney pain)

20-29:

  1. Abdominal discomfort
  2. Gallbladder disorder
  3. Nausea (feeling of having an urge to vomit)
  4. Bipolar disorder (mood disorder)
  5. Drug toxicity
  6. Polysubstance dependence
  7. Substance abuse
  8. Abdominal pain upper
  9. Accidental death
  10. Back pain

30-39:

  1. Nausea (feeling of having an urge to vomit)
  2. Salivary hypersecretion (excess saliva secretion)

40-49:

  1. Drug ineffective
  2. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  3. Dry mouth
  4. Dyspepsia (indigestion)
  5. Emotional distress
  6. Fatigue (feeling of tiredness)
  7. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  8. Hyperhidrosis (abnormally increased sweating)
  9. Influenza
  10. Insomnia (sleeplessness)

50-59:

  1. Dehydration (dryness resulting from the removal of water)
  2. Suicidal ideation

60+:

n/a

What are the existing conditions these people have? *

  1. Hepatitis C: 4 people, 26.67%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 13.33%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 13.33%
  4. Pain: 1 person, 6.67%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 6.67%
  6. Birth Control: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Adderall 10 and Excedrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Adderall 10:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Excedrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adderall 10 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Excedrin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate and acetaminophen; aspirin; caffeine (the active ingredients of Adderall 10 and Excedrin, respectively), and Adderall 10 and Excedrin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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