Adderall and Afinitor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) and Afinitor (everolimus). Common drug interactions include upper respiratory tract infection among females and aggression among males.

The phase IV clinical study analyzes what interactions people have when they take Adderall and Afinitor. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.

What is Afinitor?

Afinitor has active ingredients of everolimus. It is often used in breast cancer metastatic. eHealthMe is studying from 41,680 Afinitor users. Check the latest studies of Afinitor.



On Jul, 09, 2026

38 people who take Adderall and Afinitor together, and have interactions are studied.

Adderall and Afinitor drug interactions.

What are the common drug interactions of Adderall and Afinitor, by gender? *:

female:

  1. Upper respiratory tract infection
  2. Stomatitis (inflammation of mucous membrane of mouth)
  3. Headache (pain in head)
  4. Memory impairment
  5. Anxiety
  6. Dyspnoea (difficult or laboured respiration)
  7. Fatigue (feeling of tiredness)
  8. Eating disorder
  9. Abdominal distension
  10. Anaemia (lack of blood)

male:

  1. Aggression
  2. Mood altered (changes in mood)
  3. Abnormal behaviour
  4. Acne (skin problems that cause pimples)
  5. Alopecia (absence of hair from areas of the body)
  6. Anxiety
  7. Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
  8. Blood creatine phosphokinase increased
  9. Body temperature increased
  10. Dizziness

What are the common drug interactions of Adderall and Afinitor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Aggression
  2. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  3. Sleep disorder
  4. Body temperature increased
  5. Diarrhoea
  6. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Paranasal sinus hypersecretion
  9. Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
  10. Pyrexia (fever)

10-19:

  1. Anxiety
  2. Blood cholesterol increased
  3. Diarrhoea
  4. Epistaxis (bleed from the nose)
  5. Pneumonia
  6. Stomatitis (inflammation of mucous membrane of mouth)
  7. Cellulitis (infection under the skin)
  8. Cellulitis staphylococcal (a type of bacteria originated skin soft tissue infection)
  9. Headache (pain in head)
  10. Mood altered (changes in mood)

20-29:

  1. Stomatitis (inflammation of mucous membrane of mouth)
  2. Blood cholesterol increased
  3. Dizziness
  4. Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
  5. Blood creatine phosphokinase increased
  6. Diarrhoea
  7. Dyspnoea (difficult or laboured respiration)
  8. Fatigue (feeling of tiredness)
  9. Immunosuppression
  10. Malaise (a feeling of general discomfort or uneasiness)

30-39:

  1. Abdominal discomfort
  2. Acne (skin problems that cause pimples)
  3. Chapped lips (cracking, fissuring, and peeling of the skin f lip)
  4. Diarrhoea
  5. Dry skin
  6. Headache (pain in head)
  7. Kidney infection
  8. Lip dry
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Memory impairment

40-49:

n/a

50-59:

  1. Anxiety
  2. Dyspnoea (difficult or laboured respiration)
  3. Eating disorder
  4. Fatigue (feeling of tiredness)
  5. Stomatitis (inflammation of mucous membrane of mouth)
  6. Abdominal distension
  7. Anaemia (lack of blood)
  8. Blood cholesterol increased
  9. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  10. Haematocrit decreased

60+:

  1. Hallucination (an experience involving the perception of something not present)
  2. Abnormal dreams
  3. Malaise (a feeling of general discomfort or uneasiness)
  4. Nausea (feeling of having an urge to vomit)
  5. Pain in extremity
  6. Rash
  7. Tumour marker increased
  8. Upper respiratory tract infection
  9. Weight decreased
  10. Asthenia (weakness)

What are the existing conditions these people have? *

  1. Angiomyolipoma (most common benign tumour of the kidney): 13 people, 34.21%
  2. Brain Neoplasm Benign (non-cancerous tumour of brain): 6 people, 15.79%
  3. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 5 people, 13.16%
  4. Astrocytoma, Low Grade (low grade tumour of the brain that originate in a particular kind of glial-cells): 5 people, 13.16%
  5. Partial Seizures (seizures which affect only a part of the brain at onset): 4 people, 10.53%
  6. Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur): 3 people, 7.89%
  7. Tuberous Sclerosis (a rare genetic disease that causes benign tumours to grow in the brain and other organs): 2 people, 5.26%
  8. Benign Renal Neoplasm (benign (non-cancerous) tumours of the kidney): 2 people, 5.26%
  9. Asthma: 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Adderall and Afinitor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Adderall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Afinitor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adderall and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Afinitor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate and everolimus (the active ingredients of Adderall and Afinitor, respectively), and Adderall and Afinitor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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