Adderall and Auvelity drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) and Auvelity (bupropion hydrochloride; dextromethorphan hydrobromide). Common drug interactions include dizziness among females and adverse drug reaction among males.

The phase IV clinical study analyzes what interactions people have when they take Adderall and Auvelity. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.

What is Auvelity?

Auvelity has active ingredients of bupropion hydrochloride; dextromethorphan hydrobromide. eHealthMe is studying from 891 Auvelity users. Check the latest studies of Auvelity.

On Jul, 06, 2026

40 people who take Adderall and Auvelity together, and have interactions are studied.

Adderall and Auvelity drug interactions.

What are the common drug interactions of Adderall and Auvelity, by gender? *:

female:

Dizziness
Dissociation
Lethargy (tiredness)
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Photosensitivity reaction
Sensory disturbance (sense disturbance)
Diarrhoea
Nausea (feeling of having an urge to vomit)
Abnormal loss of weight

male:

Adverse drug reaction
Disturbance in attention
Contusion (a type of hematoma of tissue in which capillaries)
Excessive masturbation
Fall
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Tinnitus (a ringing in the ears)
Hypersomnia (excessive daytime sleepiness (eds))

What are the common drug interactions of Adderall and Auvelity, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Tinnitus (a ringing in the ears)
Agoraphobia (extreme or irrational fear of crowded spaces or enclosed public places)
Drug ineffective
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hypertension (high blood pressure)
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
Mania (a state of abnormally elevated or irritable mood)

30-39:

Abnormal loss of weight
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Confusional state
Diarrhoea
Dizziness
Food aversion (we reject certain foods for a reason)
Headache (pain in head)
Hyperhidrosis (abnormally increased sweating)
Hypoaesthesia (reduced sense of touch or sensation)
Nausea (feeling of having an urge to vomit)

40-49:

Adverse drug reaction
Drug ineffective
Mood altered (changes in mood)
Ejaculation disorder
Excessive masturbation
Dizziness
Dry mouth
Fatigue (feeling of tiredness)
Hypoacusis (loss of hearing)
Irritability

50-59:

Loss of consciousness
Abdominal pain
Acute sinusitis
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Bone atrophy (decrease in bone mass)
Breast mass
Bronchial hyperreactivity
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Colitis microscopic (inflammation of colon with diarrhoea and abdominal cramps)
Constipation

60+:

Dissociation
Dizziness
Photosensitivity reaction
Contusion (a type of hematoma of tissue in which capillaries)
Fall
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Anorgasmia (type of sexual dysfunction in which a person cannot achieve orgasm, even with adequate stimulation)
Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)

What are the existing conditions these people have? *

Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 16 people, 40.00%
Drowsiness: 4 people, 10.00%
Depression: 3 people, 7.50%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 5.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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