Adderall and Avandia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) and Avandia (rosiglitazone maleate). Common drug interactions include hypersensitivity among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Adderall and Avandia. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.

What is Avandia?

Avandia has active ingredients of rosiglitazone maleate. It is often used in diabetes. eHealthMe is studying from 142,155 Avandia users. Check the latest studies of Avandia.

On Jul, 04, 2026

34 people who take Adderall and Avandia together, and have interactions are studied.

What are the common drug interactions of Adderall and Avandia, by gender? *:

female:

Hypersensitivity
Hypoaesthesia (reduced sense of touch or sensation)
Constipation
Fall
Muscle spasms (muscle contraction)
Muscular weakness (muscle weakness)
Anxiety
Chest pain
Dyspnoea exertional (breathlessness or shortness of breath)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

male:

Anxiety
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Decreased activity
Dyspnoea (difficult or laboured respiration)
Emotional distress
Haemoglobin decreased
Heart rate decreased
Intravascular haemolysis (intravascular rupture of red blood cells with the release of haemoglobin and the cellular constituents into the plasma, or liquid portion of whole blood)

What are the common drug interactions of Adderall and Avandia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Anxiety
Bipolar disorder (mood disorder)
Cardiogenic shock (inadequate circulation of blood)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Crying
Hepatotoxicity (chemical-driven liver damage)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)

30-39:

n/a

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Blood lactate dehydrogenase increased
Decreased activity
Emotional distress
Haemoglobin decreased
Intravascular haemolysis (intravascular rupture of red blood cells with the release of haemoglobin and the cellular constituents into the plasma, or liquid portion of whole blood)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)

50-59:

Constipation
Fall
Hypersensitivity
Hypoaesthesia (reduced sense of touch or sensation)
Muscle spasms (muscle contraction)
Muscular weakness (muscle weakness)
Skeletal injury (bone and supporting muscle injury)
Tension (the act or process of stretching something tight)
Asthenia (weakness)
Atrioventricular block (heart block)

60+:

Acute myocardial infarction (acute heart attack)
Death
Cyst (a closed sac)
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Fall
Head injury
Infection
Oedema peripheral (superficial swelling)
Orthopnoea (shortness of breath (dyspnea) when lying down)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 23.53%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 23.53%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 5 people, 14.71%
Depression: 5 people, 14.71%
Stress And Anxiety: 3 people, 8.82%
Sleep Disorder: 3 people, 8.82%
Muscle Spasms (muscle contraction): 3 people, 8.82%
Hiv Infection: 3 people, 8.82%
High Blood Pressure: 3 people, 8.82%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 3 people, 8.82%

* Approximation only. Some reports may have incomplete information.

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