Adderall and Niaspan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) and Niaspan (niacin). Common drug interactions include aggression among females and flushing among males.

The phase IV clinical study analyzes what interactions people have when they take Adderall and Niaspan. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.

What is Niaspan?

Niaspan has active ingredients of niacin. It is often used in high blood cholesterol. eHealthMe is studying from 45,453 Niaspan users. Check the latest studies of Niaspan.

On Jul, 09, 2026

57 people who take Adderall and Niaspan together, and have interactions are studied.

What are the common drug interactions of Adderall and Niaspan, by gender? *:

female:

Aggression
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Blood glucose increased
Burning sensation
Confusional state
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Fall
Headache (pain in head)
Homicidal ideation (thoughts about human killing another human)

male:

Flushing (the warm, red condition of human skin)
Chronic kidney disease
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Back pain
Constipation
Cough
Dehydration (dryness resulting from the removal of water)
Drug effect decreased
Jaundice cholestatic
Mobility decreased (ability to move is reduced)

What are the common drug interactions of Adderall and Niaspan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Aggression
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Confusional state
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Fall
Fatigue (feeling of tiredness)
Homicidal ideation (thoughts about human killing another human)
Insomnia (sleeplessness)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

30-39:

Heart rate increased
Skin warm
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Rash macular (small, flat red spots)

40-49:

Flushing (the warm, red condition of human skin)
Abdominal pain upper
Affect lability (emotional incontinence)
Arthralgia (joint pain)
Blood glucose increased
Burning sensation
Coagulopathy (blood's ability to clot is impaired)
Constipation
Diarrhoea
Disturbance in attention

50-59:

Sinusitis (inflammation of sinus)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Therapeutic response unexpected
Thrombocytopenia (decrease of platelets in blood)
Tremor (trembling or shaking movements in one or more parts of your body)
Verbal abuse (abusive behaviour involving the use of language)
Vitamin d decreased
Bipolar ii disorder (characterized by at least one episode of hypomania and at least one episode of major depression)
Chronic kidney disease
Generalised anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry)

60+:

Flushing (the warm, red condition of human skin)
Drug ineffective
Blood glucose increased
Dyspnoea (difficult or laboured respiration)
Migraine (headache)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Surgery
Tinnitus (a ringing in the ears)
Blindness
Ocular vascular disorder (disease of eye blood circulation)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 24.56%
High Blood Pressure: 11 people, 19.30%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 14.04%
Insomnia (sleeplessness): 7 people, 12.28%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 6 people, 10.53%
Multiple Allergies (allergy to multiple agents): 6 people, 10.53%
Gastric Ulcer (stomach ulcer): 6 people, 10.53%
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 6 people, 10.53%
Blood Pressure Abnormal: 6 people, 10.53%
Pain: 5 people, 8.77%

* Approximation only. Some reports may have incomplete information.

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