Adderall and Zantac 75 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate) and Zantac 75 (ranitidine hydrochloride). Common drug interactions include chronic kidney disease among females and irritability among males.

The phase IV clinical study analyzes what interactions people have when they take Adderall and Zantac 75. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.

What is Zantac 75?

Zantac 75 has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 3,796 Zantac 75 users. Check the latest studies of Zantac 75.

On Jul, 06, 2026

14 people who take Adderall and Zantac 75 together, and have interactions are studied.

Adderall and Zantac 75 drug interactions.

What are the common drug interactions of Adderall and Zantac 75, by gender? *:

female:

Chronic kidney disease
Insomnia (sleeplessness)
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Confusional state
Drug ineffective
Feeling jittery
Hyperhidrosis (abnormally increased sweating)

male:

Irritability
Bipolar ii disorder (characterized by at least one episode of hypomania and at least one episode of major depression)
Renal impairment (severely reduced kidney function)
Staphylococcal infection (an infection with staphylococcus bacteria)
Type 2 diabetes mellitus
Urethral stenosis (narrowing of the urethra, may cause decreased urine output)
Urinary tract infection
Chronic kidney disease
Constipation
Dehydration (dryness resulting from the removal of water)

What are the common drug interactions of Adderall and Zantac 75, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Insomnia (sleeplessness)
Confusional state
Drug ineffective
Feeling jittery
Hyperhidrosis (abnormally increased sweating)

40-49:

n/a

50-59:

Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
Nephrolithiasis (calculi in the kidneys)
Renal impairment (severely reduced kidney function)
Staphylococcal infection (an infection with staphylococcus bacteria)
Type 2 diabetes mellitus
Urethral stenosis (narrowing of the urethra, may cause decreased urine output)
Urinary tract infection
Bipolar ii disorder (characterized by at least one episode of hypomania and at least one episode of major depression)
Chronic kidney disease
Constipation

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

What are the existing conditions these people have? *

Indigestion: 9 people, 64.29%
Inflammation: 8 people, 57.14%
Herpes Virus Infection: 7 people, 50.00%
Ammonia Abnormal: 7 people, 50.00%
Headache (pain in head): 7 people, 50.00%
Nausea (feeling of having an urge to vomit): 7 people, 50.00%
Hepatitis C: 7 people, 50.00%
Fatigue (feeling of tiredness): 7 people, 50.00%
High Blood Pressure: 2 people, 14.29%
Multiple Myeloma (cancer of the plasma cells): 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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