Adempas and Asa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adempas (riociguat) and Asa (aspirin). Common drug interactions include atelectasis among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Adempas and Asa. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Adempas?

Adempas has active ingredients of riociguat. eHealthMe is studying from 29,741 Adempas users. Check the latest studies of Adempas.

What is Asa?

Asa has active ingredients of aspirin. It is often used in blood clots. eHealthMe is studying from 32,557 Asa users. Check the latest studies of Asa.

On Jul, 13, 2026

45 people who take Adempas and Asa together, and have interactions are studied.

What are the common drug interactions of Adempas and Asa, by gender? *:

female:

Atelectasis (partial or complete collapse of the lung)
Blood urea increased
Fall
Hypoxia (low oxygen in tissues)
Loss of consciousness
Oxygen saturation decreased
Paratracheal lymphadenopathy (disease affecting the lymph nodes of para tracheal)
Pleural effusion (water on the lungs)
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
Pulmonary oedema (fluid accumulation in the lungs)

male:

Death
Nausea (feeling of having an urge to vomit)
Vomiting
Epistaxis (bleed from the nose)
Oxygen saturation decreased
Anaemia (lack of blood)
Blood pressure decreased
Constipation
Cough
Disorientation (disability in which the senses of time, direction, and recognition of people and places)

What are the common drug interactions of Adempas and Asa, by age (0-1 to 60+)? *:

0-1:

Eyelid oedema (eyelids are swollen and contain excessive fluid)
Generalised oedema (swelling all over the body)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Arteriovenous malformation

40-49:

Constipation
Cough
Dyspepsia (indigestion)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Flushing (the warm, red condition of human skin)
Heart rate increased
Chills (felling of cold)
Discomfort
Glossitis (infection of tongue with soreness)

50-59:

Hypotension (abnormally low blood pressure)
Infection
Malaise (a feeling of general discomfort or uneasiness)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nasopharyngitis (inflammation of the nasopharynx)
Neck pain
Oropharyngeal pain
Pneumonia
Rash pruritic (redness with itching)

60+:

Dyspnoea (difficult or laboured respiration)
Nausea (feeling of having an urge to vomit)
Hypotension (abnormally low blood pressure)
Procedural complication
Pulmonary hypertension (increase in blood pressure in the lung artery)
Rehabilitation therapy
Vomiting
Asthenia (weakness)
Blood pressure systolic decreased
Death

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 29 people, 64.44%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 18 people, 40.00%

* Approximation only. Some reports may have incomplete information.

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