Adrucil and Acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adrucil (fluorouracil) and Acetaminophen (acetaminophen). Common drug interactions include pancytopenia among females and dehydration among males.

The phase IV clinical study analyzes what interactions people have when they take Adrucil and Acetaminophen. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Adrucil?

Adrucil has active ingredients of fluorouracil. eHealthMe is studying from 792 Adrucil users. Check the latest studies of Adrucil.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

On Jul, 12, 2026

14 people who take Adrucil and Acetaminophen together, and have interactions are studied.

Adrucil and Acetaminophen drug interactions.

What are the common drug interactions of Adrucil and Acetaminophen, by gender? *:

female:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pneumonia
Febrile neutropenia (fever with reduced white blood cells)
Pyrexia (fever)
Blood creatinine increased
Escherichia infection (bacterial infection by escherichia coli)
Haemoglobin decreased
International normalised ratio increased
Neutropenia (an abnormally low number of neutrophils)
Urinary tract infection

male:

Dehydration (dryness resulting from the removal of water)
Diarrhoea
Hypovolaemia (a decreased volume of circulating blood in the body)
Hypoxia (low oxygen in tissues)
Ileal perforation
Ileus (a painful obstruction of the ileum or other part of the intestine)
Localised skin reaction (skin reaction at single location)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Neutropenia (an abnormally low number of neutrophils)
Night sweats (sweating in night)

What are the common drug interactions of Adrucil and Acetaminophen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Febrile neutropenia (fever with reduced white blood cells)
Dyspnoea (difficult or laboured respiration)
Flushing (the warm, red condition of human skin)
Infusion related reaction
Malaise (a feeling of general discomfort or uneasiness)

50-59:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pneumonia
Pyrexia (fever)
Anal fissure
Dehydration (dryness resulting from the removal of water)
Dermatitis radiation (inflammation of the skin due to exposure to radiation)
Diarrhoea
Febrile neutropenia (fever with reduced white blood cells)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Ileal perforation

60+:

Mucosal inflammation (infection of mucous membrane)
Neutropenia (an abnormally low number of neutrophils)
Oral discomfort (pain or irritation in mouth)
Vomiting
Weakness
Bacterial infection
Blood creatinine increased
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Ejection Fraction Decreased (systolic heart failure): 4 people, 28.57%

* Approximation only. Some reports may have incomplete information.

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