Akynzeo and Valacyclovir hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Akynzeo (netupitant; palonosetron hydrochloride) and Valacyclovir hydrochloride (valacyclovir hydrochloride). Common drug interactions include hypokalaemia among females and confusional state among males.

The phase IV clinical study analyzes what interactions people have when they take Akynzeo and Valacyclovir hydrochloride. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Akynzeo?

Akynzeo has active ingredients of netupitant; palonosetron hydrochloride. eHealthMe is studying from 1,332 Akynzeo users. Check the latest studies of Akynzeo.

What is Valacyclovir hydrochloride?

Valacyclovir hydrochloride has active ingredients of valacyclovir hydrochloride. It is often used in herpes zoster. eHealthMe is studying from 12,929 Valacyclovir hydrochloride users. Check the latest studies of Valacyclovir hydrochloride.

On Jul, 20, 2026

12 people who take Akynzeo and Valacyclovir hydrochloride together, and have interactions are studied.

Akynzeo and Valacyclovir hydrochloride drug interactions.

What are the common drug interactions of Akynzeo and Valacyclovir Hydrochloride, by gender? *:

female:

Hypokalaemia (low potassium)
Neutropenia (an abnormally low number of neutrophils)
Pneumonia
Salmonellosis (an infection with salmonella bacteria)
Dysphagia (a condition in which swallowing is difficult or painful)
Febrile neutropenia (fever with reduced white blood cells)
Hepatitis b
Pulmonary embolism (blockage of the main artery of the lung)
Diarrhoea
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)

male:

Confusional state
Dermatitis exfoliative generalised (inflammatory skin disease with erythema and scaling that affects nearly the entire cutaneous surface)
Diffuse large b-cell lymphoma (cancer of b cells, a type of white blood cell)
Hypotension (abnormally low blood pressure)
Infusion related reaction
Malignant neoplasm progression (cancer tumour came back)
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)

What are the common drug interactions of Akynzeo and Valacyclovir Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Febrile neutropenia (fever with reduced white blood cells)

50-59:

n/a

60+:

Diarrhoea
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
Hypotension (abnormally low blood pressure)
Infusion related reaction
Malignant neoplasm progression (cancer tumour came back)
Nausea (feeling of having an urge to vomit)
Pulmonary embolism (blockage of the main artery of the lung)
Pyrexia (fever)
Hypokalaemia (low potassium)
Neutropenia (an abnormally low number of neutrophils)

What are the existing conditions these people have? *

Anaemia (lack of blood): 5 people, 41.67%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 5 people, 41.67%
Multiple Myeloma (cancer of the plasma cells): 5 people, 41.67%
C-Reactive Protein Increased: 4 people, 33.33%
Dyslipidaemia (abnormal amount of lipids): 4 people, 33.33%
Eye Pain: 4 people, 33.33%
High Blood Pressure: 4 people, 33.33%
Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 33.33%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 4 people, 33.33%
Insomnia (sleeplessness): 4 people, 33.33%

* Approximation only. Some reports may have incomplete information.

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