Alavert and Bactrim drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Alavert (loratadine) and Bactrim (sulfamethoxazole; trimethoprim). Common drug interactions include metastases to bone among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Alavert and Bactrim. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Alavert?

Alavert has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 2,062 Alavert users. Check the latest studies of Alavert.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 15, 2026

24 people who take Alavert and Bactrim together, and have interactions are studied.

What are the common drug interactions of Alavert and Bactrim, by gender? *:

female:

Metastases to bone (cancer spreads to bone)
Metastases to central nervous system (cancer spreads to central nervous system)
Metastases to lymph nodes (cancer spreads to lymph node)
Microcytosis (a condition in which red blood cells are unusually small)
Mouth cyst (a fluid filled sac in mouth)
Nausea (feeling of having an urge to vomit)
Neck pain
Oedema (fluid collection in tissue)
Oral pain
Osteomyelitis (infection of bone)

male:

Fatigue (feeling of tiredness)
Abdominal discomfort
Pain
Quality of life decreased
Renal disorder (kidney disease)
Vomiting
Weight decreased
Bone density decreased
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)

What are the common drug interactions of Alavert and Bactrim, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Vomiting
Abscess (pus)
Abscess jaw (tooth abscess or root abscess)
Abscess limb (limb infection)
Activities of daily living impaired
Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
Alopecia (absence of hair from areas of the body)
Anaemia (lack of blood)
Asthenia (weakness)
Ataxia (loss of full control of bodily movements)

20-29:

Abdominal pain upper
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Depression
Gallbladder cholesterolosis (accumulation and deposition of cholesterol inside of the)

30-39:

Renal failure (kidney dysfunction)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Decreased activity
Depression
Emotional distress
Fatigue (feeling of tiredness)
Pain
Quality of life decreased
Renal disorder (kidney disease)

40-49:

Chronic kidney disease

50-59:

Bacteriuria (presence of bacteria in urine)
Blood alkaline phosphatase increased
Blood cholesterol increased
Blood triglycerides increased
Blood urea increased
Blood urine present
Bradykinesia (decreased bodily movement. it is associated with basal ganglia diseases)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cerebellar syndrome (impaired blood circulation to cerebellum due to lesion in artery)
Chronic kidney disease

60+:

Diarrhoea
Rash
Adverse event
Alopecia (absence of hair from areas of the body)
Anaemia (lack of blood)
Asthenia (weakness)
Ataxia (loss of full control of bodily movements)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Balance disorder
Blood alkaline phosphatase decreased

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 4 people, 16.67%
Pain: 4 people, 16.67%
Stress And Anxiety: 4 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 12.50%
Hiv Infection: 3 people, 12.50%
Infection: 3 people, 12.50%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 12.50%
Musculoskeletal Discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves): 2 people, 8.33%
Muscle Spasms (muscle contraction): 2 people, 8.33%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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