Alavert and Simvastatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Alavert (loratadine) and Simvastatin (simvastatin). Common drug interactions include blood glucose fluctuation among females and abdominal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Alavert and Simvastatin. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Alavert?

Alavert has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 2,062 Alavert users. Check the latest studies of Alavert.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,969 Simvastatin users. Check the latest studies of Simvastatin.



On Jul, 09, 2026

54 people who take Alavert and Simvastatin together, and have interactions are studied.

Alavert and Simvastatin drug interactions.

What are the common drug interactions of Alavert and Simvastatin, by gender? *:

female:

  1. Blood glucose fluctuation
  2. Blood testosterone decreased
  3. Bone pain
  4. Confusional state
  5. Death
  6. Depression
  7. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  8. Drug effect decreased
  9. Fall
  10. Feeling hot

male:

  1. Abdominal discomfort
  2. Diarrhoea
  3. Acute myocardial infarction (acute heart attack)
  4. Cardiac arrest
  5. Colonic obstruction (obstruction in colon)
  6. Death
  7. Fatigue (feeling of tiredness)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  10. Ulcer haemorrhage (bleeding ulcer)

What are the common drug interactions of Alavert and Simvastatin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Insomnia (sleeplessness)
  2. Sleep disorder

30-39:

n/a

40-49:

  1. Hypersensitivity

50-59:

  1. Chronic kidney disease
  2. Anxiety
  3. Renal failure (kidney dysfunction)
  4. Renal injury (kidney injury)
  5. Drug ineffective
  6. Throat tightness
  7. Depression
  8. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  9. Dysgeusia (disorder of the sense of taste)
  10. Headache (pain in head)

60+:

  1. Cytomegalovirus infection
  2. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  3. Pleural effusion (water on the lungs)
  4. Renal impairment (severely reduced kidney function)
  5. Skin cancer
  6. Transplant rejection (a transplant material is not worked)
  7. Drug ineffective
  8. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  9. Duodenal ulcer
  10. Fall

What are the existing conditions these people have? *

  1. Hypersensitivity: 12 people, 22.22%
  2. Multiple Myeloma (cancer of the plasma cells): 8 people, 14.81%
  3. High Blood Pressure: 8 people, 14.81%
  4. Diabetes: 8 people, 14.81%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 11.11%
  6. Asthma: 6 people, 11.11%
  7. Quit Smoking: 5 people, 9.26%
  8. Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 9.26%
  9. Cardiac Disorder: 5 people, 9.26%
  10. Gout (uric acid crystals building up in the body): 4 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Alavert and Simvastatin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Alavert and Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Alavert:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Alavert and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Simvastatin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on loratadine and simvastatin (the active ingredients of Alavert and Simvastatin, respectively), and Alavert and Simvastatin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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