Aleve and Felodipine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Aleve (naproxen sodium) and Felodipine (felodipine). Common drug interactions include hallucination among females and asthenia among males.
The phase IV clinical study analyzes what interactions people have when they take Aleve and Felodipine. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.
What is Aleve?
Aleve has active ingredients of naproxen sodium. It is often used in pain. eHealthMe is studying from 70,279 Aleve users. Check the latest studies of Aleve.
What is Felodipine?
Felodipine has active ingredients of felodipine. It is often used in high blood pressure. eHealthMe is studying from 15,120 Felodipine users. Check the latest studies of Felodipine.
37 people who take Aleve and Felodipine together, and have interactions are studied.

What are the common drug interactions of Aleve and Felodipine, by gender? *:
female:
- Hallucination (an experience involving the perception of something not present)
- Delusion (a false belief or opinion)
- Fatigue (feeling of tiredness)
- Hypokinesia (decreased bodily movement)
- Drug ineffective
- Abdominal pain
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Arthralgia (joint pain)
- Chest discomfort
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
male:
- Asthenia (weakness)
- Chronic kidney disease
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Anxiety
- Back pain
- Blood creatine phosphokinase increased
- Blood glucose increased
- Blood potassium decreased
- Blood urea increased
- Cardiac failure congestive
What are the common drug interactions of Aleve and Felodipine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Asthenia (weakness)
- Dizziness postural
- Faeces discoloured
- Gastritis (inflammation of stomach)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Haematemesis (vomiting of blood)
- Haematochezia (passage of stools containing blood)
- Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
- Melaena (the passage of black, tarry stools)
- Peptic ulcer
50-59:
- Chronic myeloid leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood)
- Abnormal dreams
- Anxiety
- Decreased appetite
- Disability
- Disturbance in attention
- Dysstasia (difficulty in standing)
- Emotional distress
- Memory impairment
- Mood swings (an extreme or rapid change in mood)
60+:
- Hallucination (an experience involving the perception of something not present)
- Fatigue (feeling of tiredness)
- Acute phosphate nephropathy (sudden damage to the kidneys caused by the formation of phosphate crystals)
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Back pain
- Blood creatine phosphokinase increased
- Blood glucose increased
- Blood potassium decreased
- Blood urea increased
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 13.51%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 4 people, 10.81%
- Primary Myelofibrosis (primary disorder of the bone marrow): 3 people, 8.11%
- Hallucinations (sensations that appear real but are created by your mind): 3 people, 8.11%
- Delusion (a false belief or opinion): 3 people, 8.11%
- Chronic Kidney Disease: 3 people, 8.11%
- Prostate Cancer: 2 people, 5.41%
- Hyperthyroidism (over activity of the thyroid gland): 2 people, 5.41%
- Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium): 2 people, 5.41%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 5.41%
* Approximation only. Some reports may have incomplete information.
Do you take Aleve and Felodipine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Aleve (70,279 reports)
- Felodipine (15,120 reports)
Browse all drug interactions of Aleve and Felodipine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Aleve:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Felodipine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Aleve and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Felodipine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on naproxen sodium and felodipine (the active ingredients of Aleve and Felodipine, respectively), and Aleve and Felodipine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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