Algin and Diphen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Algin (algin) and Diphen (diphenhydramine hydrochloride). Common drug interactions include cystitis among females and cytomegalovirus infection among males.

The phase IV clinical study analyzes what interactions people have when they take Algin and Diphen. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Algin?

Algin has active ingredients of algin. eHealthMe is studying from 1,584 Algin users. Check the latest studies of Algin.

What is Diphen?

Diphen has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 115,432 Diphen users. Check the latest studies of Diphen.



On Jul, 14, 2026

35 people who take Algin and Diphen together, and have interactions are studied.

Algin and Diphen drug interactions.

What are the common drug interactions of Algin and Diphen, by gender? *:

female:

  1. Cystitis (inflammation of the wall of the bladder)
  2. Diarrhoea
  3. Dyslexia (disorders that involve difficulty in learning to read or interpret words, letters, and other symbols)
  4. Dyspepsia (indigestion)
  5. Erythema (redness of the skin)
  6. Fungal infection
  7. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  8. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  9. Viral infection
  10. Nausea (feeling of having an urge to vomit)

male:

  1. Cytomegalovirus infection
  2. Decreased appetite
  3. White blood cell count decreased
  4. Abdominal pain
  5. Blood creatinine increased
  6. Back pain
  7. Fatigue (feeling of tiredness)
  8. Lymphocyte count decreased
  9. Urinary tract infection
  10. Diarrhoea

What are the common drug interactions of Algin and Diphen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Cytomegalovirus infection
  2. Decreased appetite
  3. Diarrhoea
  4. Dysuria (painful or difficult urination)
  5. Lymphopenia (an abnormally low level of lymphocytes in the blood)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Pain in extremity
  8. Proctalgia (pain in the rectum)
  9. Pyrexia (fever)
  10. Tremor (trembling or shaking movements in one or more parts of your body)

40-49:

  1. Pneumonia

50-59:

  1. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  2. Abdominal pain
  3. Bladder pain
  4. Colitis (inflammation of colon)
  5. Urinary tract infection

60+:

  1. Cataract (clouding of the lens inside the eye)
  2. Fall
  3. Vulvovaginal candidiasis (vulvovaginal infection by fungi)
  4. Cough
  5. Lower respiratory tract infection
  6. Nasopharyngitis (inflammation of the nasopharynx)
  7. Viral infection
  8. Burning sensation
  9. Crying
  10. Drug hypersensitivity

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 17 people, 48.57%
  2. Asthma: 5 people, 14.29%
  3. Constipation: 5 people, 14.29%
  4. Depression: 5 people, 14.29%
  5. Urinary Tract Infection: 4 people, 11.43%
  6. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 4 people, 11.43%
  7. Blood Bicarbonate Decreased: 4 people, 11.43%
  8. Cytomegalovirus Infection: 4 people, 11.43%
  9. Fluid Intake Reduced: 4 people, 11.43%
  10. Immunodeficiency Disorders: 4 people, 11.43%

* Approximation only. Some reports may have incomplete information.

Do you take Algin and Diphen?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Algin and Diphen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Algin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Diphen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Algin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Diphen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on algin and diphenhydramine hydrochloride (the active ingredients of Algin and Diphen, respectively), and Algin and Diphen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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