Allegra allergy and Trikafta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Allegra allergy (fexofenadine hydrochloride) and Trikafta (elexacaftor, ivacaftor, tezacaftor; ivacaftor). Common drug interactions include aphonia among females and hospitalisation among males.

The phase IV clinical study analyzes what interactions people have when they take Allegra allergy and Trikafta. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Allegra allergy?

Allegra allergy has active ingredients of fexofenadine hydrochloride. It is often used in allergies. eHealthMe is studying from 13,594 Allegra allergy users. Check the latest studies of Allegra allergy.

What is Trikafta?

Trikafta has active ingredients of elexacaftor, ivacaftor, tezacaftor; ivacaftor. eHealthMe is studying from 11,852 Trikafta users. Check the latest studies of Trikafta.

On Jul, 15, 2026

27 people who take Allegra allergy and Trikafta together, and have interactions are studied.

Allegra allergy and Trikafta drug interactions.

What are the common drug interactions of Allegra Allergy and Trikafta, by gender? *:

female:

Aphonia (inability to produce voice)
Cystic fibrosis (disease of the secretary glands)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Infection
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Rash
Cough
Dysphagia (a condition in which swallowing is difficult or painful)
Larynx irritation
Pain

male:

Hospitalisation
Productive cough
Abdominal discomfort
Abdominal pain upper
Diarrhoea
Faeces discoloured
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Nasopharyngitis (inflammation of the nasopharynx)
Urticaria (rash of round, red welts on the skin that itch intensely)

What are the common drug interactions of Allegra Allergy and Trikafta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Rash
Cystic fibrosis (disease of the secretary glands)
Pain
Pruritus (severe itching of the skin)
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Infection
Rash pruritic (redness with itching)
Arthralgia (joint pain)
Arthropathy
Pneumonia pseudomonal (pseudomonas pneumonia is an infection caused by the microbe known as pseudomonas aeruginosa)

10-19:

Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Nasopharyngitis (inflammation of the nasopharynx)
Productive cough

20-29:

Cough
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Maternal exposure during pregnancy (use of substance during pregnancy)
Pneumonia

30-39:

Crying
Cystic fibrosis (disease of the secretary glands)
Device occlusion
Dry eye (lack of adequate tears)
Dyspnoea (difficult or laboured respiration)
Eye pain
Infection
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)

40-49:

n/a

50-59:

Chest pain
Faeces discoloured
Rhinorrhoea (watery mucus discharge from the nose)

60+:

n/a

What are the existing conditions these people have? *

Cystic Fibrosis (disease of the secretary glands): 24 people, 88.89%
Asthma: 4 people, 14.81%
Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 3 people, 11.11%
Cystic Fibrosis Lung (fibrosis with cyst in the lung): 3 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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