Alphagan and Tropicamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Alphagan (brimonidine tartrate) and Tropicamide (tropicamide). Common drug interactions include eye disorder among females and eye disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Alphagan and Tropicamide. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Alphagan?

Alphagan has active ingredients of brimonidine tartrate. It is often used in glaucoma. eHealthMe is studying from 9,981 Alphagan users. Check the latest studies of Alphagan.

What is Tropicamide?

Tropicamide has active ingredients of tropicamide. eHealthMe is studying from 1,529 Tropicamide users. Check the latest studies of Tropicamide.



On Aug, 01, 2026

27 people who take Alphagan and Tropicamide together, and have interactions are studied.

Alphagan and Tropicamide drug interactions.

What are the common drug interactions of Alphagan and Tropicamide, by gender? *:

female:

  1. Eye disorder
  2. Inflammation
  3. Bacterial test positive
  4. Cutis laxa (connective tissue disorder in which the skin lacks elasticity and hangs in loose folds)
  5. Drug ineffective
  6. Post procedural complication
  7. Toxic anterior segment syndrome
  8. Vision blurred
  9. Visual acuity reduced (reduced clearness of vision)
  10. Vitreous floaters (spots before the eyes)

male:

  1. Eye disorder
  2. Inflammation
  3. Hypertension (high blood pressure)
  4. Intracranial aneurysm (bulging, weak area in the wall of a cranial artery)
  5. Intraocular pressure increased
  6. Ocular hyperaemia (an abnormally large amount of blood in eye)
  7. Pain
  8. Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)
  9. Cardiac arrest
  10. Cardiac disorder

What are the common drug interactions of Alphagan and Tropicamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Eye disorder
  2. Eye haemorrhage (bleeding in the eye)
  3. Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
  4. Hypertension (high blood pressure)
  5. Intracranial aneurysm (bulging, weak area in the wall of a cranial artery)
  6. Intraocular pressure increased
  7. Ocular hyperaemia (an abnormally large amount of blood in eye)
  8. Pain
  9. Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)
  10. Ear infection

40-49:

n/a

50-59:

n/a

60+:

  1. Inflammation
  2. Eye disorder
  3. Post procedural complication
  4. Toxic anterior segment syndrome
  5. Bacterial test positive
  6. Chronic kidney disease
  7. Renal injury (kidney injury)

What are the existing conditions these people have? *

  1. Diabetic Retinopathy (damage to the retina caused by complications of diabetes): 3 people, 11.11%
  2. Vitreous Haemorrhage (intraocular (inside the eye) bleeding): 2 people, 7.41%
  3. Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Alphagan and Tropicamide?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Alphagan and Tropicamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Alphagan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tropicamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Alphagan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tropicamide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on brimonidine tartrate and tropicamide (the active ingredients of Alphagan and Tropicamide, respectively), and Alphagan and Tropicamide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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