Alupent and Flonase drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Alupent (metaproterenol sulfate) and Flonase (fluticasone propionate). Common drug interactions include sudden cardiac death among females and cough among males.

The phase IV clinical study analyzes what interactions people have when they take Alupent and Flonase. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Alupent?

Alupent has active ingredients of metaproterenol sulfate. eHealthMe is studying from 604 Alupent users. Check the latest studies of Alupent.

What is Flonase?

Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.

On Jul, 07, 2026

23 people who take Alupent and Flonase together, and have interactions are studied.

What are the common drug interactions of Alupent and Flonase, by gender? *:

female:

Sudden cardiac death
Alanine aminotransferase increased
Arrhythmia (irregular heartbeat)
Cardiac arrest
Chronic obstructive airways disease
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
International normalised ratio increased
Activated partial thromboplastin time prolonged
Acute myocardial infarction (acute heart attack)
Platelet count decreased

male:

Cough
Nocturnal dyspnoea (attacks of severe shortness of breath and coughing that generally occur at night)
Tooth disorder (tooth disease)

What are the common drug interactions of Alupent and Flonase, by age (0-1 to 60+)? *:

0-1:

Anxiety
Asthma
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Fungal infection
Pyrexia (fever)
Stomatitis (inflammation of mucous membrane of mouth)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Herpes simplex (herpes simplex is a common viral infection)
Vaginitis (inflammation of the vagina)

40-49:

n/a

50-59:

Band neutrophil count increased
Blood alkaline phosphatase nos increased
Blood calcium decreased
Blood carbon dioxide decreased
Blood urea increased
Cardiac disorder
Colonic haemorrhage (bleeding in colon)
Depression
Eosinophil count decreased
Haematocrit

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Malignant neoplasm progression (cancer tumour came back)
Muscle spasms (muscle contraction)
Nasopharyngitis (inflammation of the nasopharynx)
Nausea (feeling of having an urge to vomit)
Onychoclasis (breaking of the nails)
Pruritus (severe itching of the skin)
Skin burning sensation
Skin exfoliation (removal of the oldest dead skin cells)

What are the existing conditions these people have? *

Neck Pain: 2 people, 8.70%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Alupent and Flonase?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously