Ambien and Maxitrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ambien (zolpidem tartrate) and Maxitrol (dexamethasone; neomycin sulfate; polymyxin b sulfate). Common drug interactions include eye swelling among females and conjunctival hyperaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Ambien and Maxitrol. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.

What is Maxitrol?

Maxitrol has active ingredients of dexamethasone; neomycin sulfate; polymyxin b sulfate. eHealthMe is studying from 986 Maxitrol users. Check the latest studies of Maxitrol.



On Jul, 10, 2026

16 people who take Ambien and Maxitrol together, and have interactions are studied.

Ambien and Maxitrol drug interactions.

What are the common drug interactions of Ambien and Maxitrol, by gender? *:

female:

  1. Eye swelling
  2. Lacrimation increased
  3. Metastases to liver (cancer spreads to liver)
  4. Nausea (feeling of having an urge to vomit)
  5. Neoplasm malignant (cancer tumour)
  6. Visual acuity reduced (reduced clearness of vision)
  7. Aortic arteriosclerosis (hardening of the aortic arteries)
  8. Bone loss
  9. Chest discomfort
  10. Corneal oedema (corneal swelling)

male:

  1. Conjunctival hyperaemia (congestion of conjunctival vessels)
  2. Corneal opacity (scarring or clouding of the cornea)
  3. Corneal scar (nullah)
  4. Corneal thinning
  5. Eye inflammation
  6. Eye irritation
  7. Eye pain
  8. Flat anterior chamber of eye
  9. Impaired driving ability
  10. Impaired work ability

What are the common drug interactions of Ambien and Maxitrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Aortic arteriosclerosis (hardening of the aortic arteries)
  2. Aortic calcification (aortic calcification sign of heart valve disease)
  3. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
  4. Arthralgia (joint pain)
  5. Arthropathy
  6. Asthenia (weakness)
  7. Atelectasis (partial or complete collapse of the lung)
  8. Back pain
  9. Balance disorder
  10. Bladder dilatation

50-59:

  1. Instillation site irritation

60+:

  1. Corneal oedema (corneal swelling)
  2. Toxic anterior segment syndrome
  3. Injection site pain
  4. Migraine (headache)
  5. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  6. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  7. Nausea (feeling of having an urge to vomit)
  8. Neck pain
  9. Oropharyngeal pain
  10. Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

  1. Pain: 3 people, 18.75%
  2. Indigestion: 2 people, 12.50%
  3. Nausea (feeling of having an urge to vomit): 2 people, 12.50%
  4. Mydriasis (a dilation of the pupil): 2 people, 12.50%
  5. Dry Eyes (lack of adequate tears): 2 people, 12.50%
  6. Wheezing (a high-pitched whistling sound made while you breath): 1 person, 6.25%
  7. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 6.25%
  8. Blood Glucose Abnormal: 1 person, 6.25%
  9. Constipation: 1 person, 6.25%
  10. Diarrhea: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ambien and Maxitrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ambien:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Maxitrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ambien and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Maxitrol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on zolpidem tartrate and dexamethasone; neomycin sulfate; polymyxin b sulfate (the active ingredients of Ambien and Maxitrol, respectively), and Ambien and Maxitrol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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