Ceftazidime and Soliris drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ceftazidime (ceftazidime) and Soliris (eculizumab). Common drug interactions include cognitive disorder among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Ceftazidime and Soliris. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Ceftazidime?

Ceftazidime has active ingredients of ceftazidime. eHealthMe is studying from 10,327 Ceftazidime users. Check the latest studies of Ceftazidime.

What is Soliris?

Soliris has active ingredients of eculizumab. It is often used in paroxysmal nocturnal hemoglobinuria (pnh). eHealthMe is studying from 58,821 Soliris users. Check the latest studies of Soliris.



On Jul, 10, 2026

38 people who take Ceftazidime and Soliris together, and have interactions are studied.

Ceftazidime and Soliris drug interactions.

What are the common drug interactions of Ceftazidime and Soliris, by gender? *:

female:

  1. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  2. Colostomy
  3. Cytomegalovirus enterocolitis (virus infection of intestine and colon)
  4. Dysphagia (a condition in which swallowing is difficult or painful)
  5. Dyspnoea (difficult or laboured respiration)
  6. Encephalopathy (functioning of the brain is affected by some agent or condition)
  7. General physical health deterioration (weak health status)
  8. Hemiparesis (weakness on one side of the body)
  9. Intestinal perforation (complete penetration of the wall of the intestine)
  10. Pseudomonal bacteraemia (p. aeruginosa cause of bacterial infections of the blood)

male:

  1. Anaemia (lack of blood)
  2. Blood bilirubin increased
  3. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  4. Diarrhoea
  5. Hepatic enzyme increased
  6. Nausea (feeling of having an urge to vomit)
  7. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  8. Respiratory distress (difficulty in breathing)
  9. Venoocclusive liver disease (small veins in the liver are obstructed)
  10. Vomiting

What are the common drug interactions of Ceftazidime and Soliris, by age (0-1 to 60+)? *:

0-1:

  1. Pneumonia klebsiella (pneumonia caused by bacteria klebsiella)
  2. Renal impairment (severely reduced kidney function)
  3. Staphylococcal infection (an infection with staphylococcus bacteria)
  4. Pneumonia
  5. Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
  6. Pulmonary hypertension (increase in blood pressure in the lung artery)
  7. Aortic thrombosis (formation of a blood clot inside aorta)
  8. Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
  9. Fungal peritonitis (fungal infection silk like membrane lines inner abdominal wall)
  10. Intra-abdominal haemorrhage (intra-abdominal bleeding)

2-9:

  1. Acute respiratory failure
  2. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  3. Diarrhoea
  4. Hepatic enzyme increased
  5. Nausea (feeling of having an urge to vomit)
  6. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  7. Respiratory distress (difficulty in breathing)
  8. Venoocclusive liver disease (small veins in the liver are obstructed)
  9. Vomiting
  10. Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)

10-19:

  1. Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
  2. Drug ineffective
  3. Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
  4. Cytomegalovirus infection
  5. Respiratory failure (inadequate gas exchange by the respiratory system)
  6. Chronic granulomatous disease (immune system cells are unable to kill some types of bacteria and fungi)
  7. Colostomy
  8. General physical health deterioration (weak health status)
  9. Intestinal perforation (complete penetration of the wall of the intestine)
  10. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)

20-29:

  1. Anaemia (lack of blood)
  2. Blood bilirubin increased
  3. Cellulitis (infection under the skin)
  4. Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
  5. Lymphadenopathy mediastinal (an enlargement of the lymph nodes in the part of the chest that separates the lungs)
  6. Nasopharyngitis (inflammation of the nasopharynx)
  7. Neutropenia (an abnormally low number of neutrophils)
  8. Peripheral vascular disorder
  9. Renal failure chronic (long lasting kidney dysfunction)

30-39:

  1. Heparin-induced thrombocytopenia
  2. Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
  3. Large intestine perforation (hole in large intestine)
  4. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
  5. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  6. Cytomegalovirus enterocolitis (virus infection of intestine and colon)
  7. Dysphagia (a condition in which swallowing is difficult or painful)
  8. Encephalopathy (functioning of the brain is affected by some agent or condition)
  9. Hemiparesis (weakness on one side of the body)

40-49:

  1. Asthenia (weakness)
  2. Balance disorder
  3. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  4. Dehydration (dryness resulting from the removal of water)
  5. Fall
  6. Fatigue (feeling of tiredness)
  7. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
  8. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
  9. Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
  10. Ascites (accumulation of fluid in the abdominal cavity)

50-59:

  1. Cellulitis (infection under the skin)
  2. Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
  3. Lymphadenopathy mediastinal (an enlargement of the lymph nodes in the part of the chest that separates the lungs)
  4. Neutropenia (an abnormally low number of neutrophils)
  5. Peripheral vascular disorder
  6. Renal failure chronic (long lasting kidney dysfunction)
  7. Back pain
  8. Bacterial sepsis
  9. Coma (state of unconsciousness lasting more than six hours)
  10. Drug ineffective

60+:

  1. Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
  2. Haematocrit decreased
  3. Haemoglobin decreased
  4. Lymphocyte count decreased
  5. Monocyte count decreased
  6. Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
  7. Platelet count decreased
  8. Multi-organ failure (multisystem organ failure)

What are the existing conditions these people have? *

  1. Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 18 people, 47.37%
  2. Thrombotic Microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury): 7 people, 18.42%
  3. High Blood Pressure: 7 people, 18.42%
  4. Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 4 people, 10.53%
  5. Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 4 people, 10.53%
  6. Acute Kidney Failure: 3 people, 7.89%
  7. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 3 people, 7.89%
  8. Cellulitis (infection under the skin): 3 people, 7.89%
  9. Pain: 3 people, 7.89%
  10. Diabetes: 3 people, 7.89%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ceftazidime and Soliris:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ceftazidime:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Soliris:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ceftazidime and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Soliris and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ceftazidime and eculizumab (the active ingredients of Ceftazidime and Soliris, respectively), and Ceftazidime and Soliris (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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