Lupron and Votrient drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lupron (leuprolide acetate) and Votrient (pazopanib hydrochloride). Common drug interactions include death among females and diarrhoea among males.
The phase IV clinical study analyzes what interactions people have when they take Lupron and Votrient. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Lupron?
Lupron has active ingredients of leuprolide acetate. It is often used in endometriosis. eHealthMe is studying from 42,122 Lupron users. Check the latest studies of Lupron.
What is Votrient?
Votrient has active ingredients of pazopanib hydrochloride. It is often used in metastatic renal cell carcinoma. eHealthMe is studying from 25,347 Votrient users. Check the latest studies of Votrient.
12 people who take Lupron and Votrient together, and have interactions are studied.
What are the common drug interactions of Lupron and Votrient, by gender? *:
female:
- Death
- Hospitalisation
- Nail discolouration (change in nail colour)
- Nausea (feeling of having an urge to vomit)
- White blood cell count decreased
male:
- Diarrhoea
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Lip pain
- Malignant neoplasm progression (cancer tumour came back)
- Oral pain
- Stomatitis (inflammation of mucous membrane of mouth)
- Tongue disorder (disease of tongue)
- Anaemia (lack of blood)
- Asthenia (weakness)
- Cheilitis (infection of lips)
What are the common drug interactions of Lupron and Votrient, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Death
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Nail discolouration (change in nail colour)
- Nausea (feeling of having an urge to vomit)
- White blood cell count decreased
60+:
- Dysphagia (a condition in which swallowing is difficult or painful)
- Gingival erythema (redness of gums)
- Asthenia (weakness)
- Cheilitis (infection of lips)
- Diarrhoea
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Solar dermatitis (a condition in which a person develops a rash after exposure to sunlight)
- Gingival pain (gum pain)
- Glossodynia (a burning or painful sensation in the tongue)
- Headache (pain in head)
What are the existing conditions these people have? *
- Renal Cell Carcinoma (a kidney cancer): 5 people, 41.67%
- Prostate Cancer: 4 people, 33.33%
- Rhabdomyosarcoma (cancer of the bone, soft tissues, or connective tissue (e.g., tendon or cartilage)): 1 person, 8.33%
- Neoplasm Malignant (cancer tumour): 1 person, 8.33%
- Breast Cancer: 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Lupron and Votrient?
- Personalize this study to your gender, age, symptoms and drugs
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Lupron and Votrient:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lupron:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Votrient:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lupron and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Votrient and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Sharma SP, Muggia F, "Supraventricular tachycardia and urticaria complicating leuprolide-induced ovarian suppression in a young woman with breast cancer: a case report", ecancermedicalscience, 2016 Jan .
- Pong YH, Lu YC, Tsai VF, Huang PL, Hsieh JT, Chang HC, "Acute manic and psychotic symptoms following subcutaneous leuprolide acetate in a male patient without prior psychiatric history: A case report and literature review", Urological Science, 2014 Mar .
- Costa DA, de Almeida SB, Barata PC, Quintela A, Cabral P, Afonso A, Silva JM, "Pazopanib-Induced Cutaneous Leukocytoclastic Vasculitis: An Exclusion Diagnosis of a Multidisciplinary Approach", Case Reports in Oncology, 2013 Jan .
- Sharma SP, Muggia F, "Supraventricular tachycardia and urticaria complicating leuprolide-induced ovarian suppression in a young woman with breast cancer: a case report", ecancermedicalscience, 2016 Jan .
- Pong YH, Lu YC, Tsai VF, Huang PL, Hsieh JT, Chang HC, "Acute manic and psychotic symptoms following subcutaneous leuprolide acetate in a male patient without prior psychiatric history: A case report and literature review", Urological Science, 2014 Mar .
- Costa DA, de Almeida SB, Barata PC, Quintela A, Cabral P, Afonso A, Silva JM, "Pazopanib-Induced Cutaneous Leukocytoclastic Vasculitis: An Exclusion Diagnosis of a Multidisciplinary Approach", Case Reports in Oncology, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on leuprolide acetate and pazopanib hydrochloride (the active ingredients of Lupron and Votrient, respectively), and Lupron and Votrient (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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