Ambien and Psyllium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ambien (zolpidem tartrate) and Psyllium (blond psyllium). Common drug interactions include muscle spasms among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Ambien and Psyllium. It is created by eHealthMe based on reports of 86 people who take the same drugs from the FDA, and is updated regularly.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.

What is Psyllium?

Psyllium has active ingredients of blond psyllium. It is often used in constipation. eHealthMe is studying from 4,262 Psyllium users. Check the latest studies of Psyllium.

On Jul, 28, 2026

86 people who take Ambien and Psyllium together, and have interactions are studied.

What are the common drug interactions of Ambien and Psyllium, by gender? *:

female:

Muscle spasms (muscle contraction)
Muscular weakness (muscle weakness)
Headache (pain in head)
Joint range of motion decreased (disease of joint movement)
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
Neuralgia (pain in one or more nerves)
Diarrhoea
Arthralgia (joint pain)
Decreased appetite
Pneumonia

male:

Anxiety
Fall
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pyrexia (fever)
Respiratory failure (inadequate gas exchange by the respiratory system)
Vomiting
General physical health deterioration (weak health status)
Osteomyelitis (infection of bone)
Pleural effusion (water on the lungs)
Decreased appetite

What are the common drug interactions of Ambien and Psyllium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Back disorder
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
Lung disorder (lung disease)
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
Nephrolithiasis (calculi in the kidneys)
Pain
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

20-29:

n/a

30-39:

Abnormal behaviour
Aggression
Agitation (state of anxiety or nervous excitement)
Hallucination, auditory (perceiving sounds without auditory stimulus)
Suicidal behaviour
Toothache (tooth pain)

40-49:

Acute myocardial infarction (acute heart attack)
Anaemia (lack of blood)
Anxiety
Arthralgia (joint pain)
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Back pain
Bone disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cerebral haemorrhage (bleeding within the brain)

50-59:

Pain
Pneumonia
Vomiting
Actinomycosis (infection that causes sores, or abscesses)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Alopecia (absence of hair from areas of the body)
Anaemia of malignant disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Ankle fracture

60+:

Fatigue (feeling of tiredness)
Diarrhoea
Neuralgia (pain in one or more nerves)
Fall
Headache (pain in head)
Hypoxia (low oxygen in tissues)
Arthralgia (joint pain)
Hypoaesthesia (reduced sense of touch or sensation)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Oedema peripheral (superficial swelling)

What are the existing conditions these people have? *

Bone Loss: 14 people, 16.28%
Osteoporosis (bones weak and more likely to break): 14 people, 16.28%
Multiple Myeloma (cancer of the plasma cells): 11 people, 12.79%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 9 people, 10.47%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 9.30%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 7 people, 8.14%
Pain: 7 people, 8.14%
Depression: 7 people, 8.14%
High Blood Pressure: 7 people, 8.14%
Rickets (softening of bones): 7 people, 8.14%

* Approximation only. Some reports may have incomplete information.

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