Amikacin sulfate and Acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amikacin sulfate (amikacin sulfate) and Acetaminophen (acetaminophen). Common drug interactions include bronchitis among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Amikacin sulfate and Acetaminophen. It is created by eHealthMe based on reports of 100 people who take the same drugs from the FDA, and is updated regularly.

What is Amikacin sulfate?

Amikacin sulfate has active ingredients of amikacin sulfate. eHealthMe is studying from 2,538 Amikacin sulfate users. Check the latest studies of Amikacin sulfate.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

100 people who take Amikacin sulfate and Acetaminophen together, and have interactions are studied.

Amikacin sulfate and Acetaminophen drug interactions.

What are the common drug interactions of Amikacin Sulfate and Acetaminophen, by gender? *:

female:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cholecystitis (infection of gallbladder)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Device occlusion
Dyspnoea (difficult or laboured respiration)
Febrile neutropenia (fever with reduced white blood cells)
Hypophagia (reduced food intake)
Intestinal obstruction
Mucosal inflammation (infection of mucous membrane)
Oxygen saturation decreased

male:

Pyrexia (fever)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Chills (felling of cold)
Face oedema (swelling of face)
Febrile neutropenia (fever with reduced white blood cells)
Malaise (a feeling of general discomfort or uneasiness)
Pruritus (severe itching of the skin)
Rotavirus infection
Staphylococcal infection (an infection with staphylococcus bacteria)
Urticaria (rash of round, red welts on the skin that itch intensely)

What are the common drug interactions of Amikacin Sulfate and Acetaminophen, by age (0-1 to 60+)? *:

0-1:

Gastroenteritis (inflammation of stomach and intestine)
Haematemesis (vomiting of blood)
Diarrhoea

2-9:

Drug hypersensitivity
Hyperthermia (body temperature greatly above normal)
Anaphylactic reaction (serious allergic reaction)
Blood pressure decreased
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Dyspnoea (difficult or laboured respiration)
Face oedema (swelling of face)
Pruritus (severe itching of the skin)
Pyrexia (fever)
Rotavirus infection

10-19:

Febrile neutropenia (fever with reduced white blood cells)
Pulmonary oedema (fluid accumulation in the lungs)
Renal failure acute (rapid kidney dysfunction)
Pyrexia (fever)
Capillary leak syndrome (capillary leaks plasma)
Sepsis (a severe blood infection that can lead to organ failure and death)
Acidosis (build-up of carbon dioxide in the blood)
Activated partial thromboplastin time prolonged
Caecitis (inflammation of the cecum)
Chills (felling of cold)

20-29:

Chills (felling of cold)
Fatigue (feeling of tiredness)
Infection
Infusion related reaction
Pneumonia
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Pyrexia (fever)
Respiratory tract infection
Urinary tract infection
Aspergillosis (an infection caused by a fungus called aspergillus)

30-39:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Device occlusion
Intestinal obstruction
Nausea (feeling of having an urge to vomit)
Pancreatitis acute (sudden inflammation of pancreas)
Pneumonia fungal
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Rash
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)

40-49:

Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Pyrexia (fever)
Rash
Blood beta-d-glucan increased
Cystitis haemorrhagic (blood in the urine and painful voiding)
Haematuria (presence of blood in urine)
Haemoglobin decreased
Hydronephrosis (water inside the kidney)
Nasopharyngitis (inflammation of the nasopharynx)
Neutropenia (an abnormally low number of neutrophils)

50-59:

Oxygen saturation decreased
Pancreatitis (inflammation of pancreas)
Personality change
Sepsis (a severe blood infection that can lead to organ failure and death)
Somnolence (a state of near-sleep, a strong desire for sleep)
Spinal compression fracture (fracture due to spinal compression on bone)
Thrombocytopenia (decrease of platelets in blood)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Blood disorder
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

60+:

Pyrexia (fever)
Anaemia (lack of blood)
Dermo-hypodermitis (skin and subcutaneous tissue bacterial infections)
Dyschezia (difficulty in defecating)
Gait disturbance
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Glossoptosis
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Lung disorder (lung disease)

What are the existing conditions these people have? *

Fever: 19 people, 19.00%
Abdominal Pain: 15 people, 15.00%
Infection: 15 people, 15.00%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 14 people, 14.00%
High Blood Pressure: 11 people, 11.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 11.00%
Asthma: 9 people, 9.00%
Constipation: 9 people, 9.00%
Insomnia (sleeplessness): 9 people, 9.00%
Oedema (fluid collection in tissue): 8 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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