Amitriptyline hydrochloride and Simvastatin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Amitriptyline hydrochloride (amitriptyline hydrochloride) and Simvastatin (simvastatin). Common drug interactions include myocardial infarction among females and malaise among males.
The phase IV clinical study analyzes what interactions people have when they take Amitriptyline hydrochloride and Simvastatin. It is created by eHealthMe based on reports of 1,242 people who take the same drugs from the FDA, and is updated regularly.
What is Amitriptyline hydrochloride?
Amitriptyline hydrochloride has active ingredients of amitriptyline hydrochloride. It is often used in migraine. eHealthMe is studying from 20,054 Amitriptyline hydrochloride users. Check the latest studies of Amitriptyline hydrochloride.
What is Simvastatin?
Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,969 Simvastatin users. Check the latest studies of Simvastatin.
1,242 people who take Amitriptyline hydrochloride and Simvastatin together, and have interactions are studied.

What are the common drug interactions of Amitriptyline hydrochloride and Simvastatin, by gender? *
What are the common drug interactions of Amitriptyline hydrochloride and Simvastatin, by age (0-1 to 60+)? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Amitriptyline hydrochloride and Simvastatin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Amitriptyline hydrochloride (20,054 reports)
- Simvastatin (256,969 reports)
Browse all drug interactions of Amitriptyline hydrochloride and Simvastatin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Amitriptyline hydrochloride:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Simvastatin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Amitriptyline hydrochloride and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Simvastatin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Li W, Lamichhane J, "From Heartbreak to Left Bundle Branch Block: A Case of Amitriptyline Overdose", American Journal of Therapeutics, 2017 Sep .
- Li W, Lamichhane J, "From Heartbreak to Left Bundle Branch Block: A Case of Amitriptyline Overdose", American Journal of Therapeutics, 2017 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on amitriptyline hydrochloride and simvastatin (the active ingredients of Amitriptyline hydrochloride and Simvastatin, respectively), and Amitriptyline hydrochloride and Simvastatin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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