Amlodipine and Pentacarinat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amlodipine (amlodipine besylate) and Pentacarinat (pentamidine isethionate). Common drug interactions include gait disturbance among females and rash among males.

The phase IV clinical study analyzes what interactions people have when they take Amlodipine and Pentacarinat. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.

What is Amlodipine?

Amlodipine has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 354,829 Amlodipine users. Check the latest studies of Amlodipine.

What is Pentacarinat?

Pentacarinat has active ingredients of pentamidine isethionate. eHealthMe is studying from 1,546 Pentacarinat users. Check the latest studies of Pentacarinat.



On Jul, 18, 2026

79 people who take Amlodipine and Pentacarinat together, and have interactions are studied.

Amlodipine and Pentacarinat drug interactions.

What are the common drug interactions of Amlodipine and Pentacarinat, by gender? *:

female:

  1. Gait disturbance
  2. Gamma-glutamyltransferase increased
  3. Hydrocephalus (water on the brain)
  4. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  5. Leukopenia (less number of white blood cells in blood)
  6. Lymphocyte count decreased
  7. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  8. Nausea (feeling of having an urge to vomit)
  9. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  10. Plasma cell myeloma (cancer that begins in plasma cells)

male:

  1. Rash
  2. Diarrhoea
  3. Urinary tract infection
  4. Abdominal pain
  5. Back pain
  6. C-reactive protein increased
  7. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  8. Pyelonephritis (inflammation of kidney caused by bacteria)
  9. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

What are the common drug interactions of Amlodipine and Pentacarinat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Graft loss (graft failure)
  2. Hypotension (abnormally low blood pressure)
  3. Shunt occlusion (blockage of shunt)

20-29:

  1. Abdominal pain
  2. Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
  3. Balance disorder
  4. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  5. Coma (state of unconsciousness lasting more than six hours)
  6. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  7. Diarrhoea
  8. Gait disturbance
  9. Hydrocephalus (water on the brain)
  10. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

30-39:

  1. Renal insufficiency (insufficient excretion of wastes by the kidneys)
  2. Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
  3. Urinary retention (the inability to completely or partially empty the bladder)
  4. Coma (state of unconsciousness lasting more than six hours)

40-49:

  1. Acute graft versus host disease in intestine (acute complication in intestine following an allogeneic tissue/blood transplant)
  2. Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant)
  3. Acute pulmonary oedema (sudden deposit of fluid in the lung))
  4. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  5. Pneumonia escherichia (pneumonia due to bacteria escherichia coli)
  6. Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
  7. Tumour pain

50-59:

  1. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  2. Asthenia (weakness)
  3. Febrile neutropenia (fever with reduced white blood cells)
  4. Folliculitis (infection of hair root)
  5. Hallucinations, mixed (sensations that appear real but are created by your mind -mixed)
  6. Phlebitis (inflammation of the walls of a vein)
  7. Staphylococcal infection (an infection with staphylococcus bacteria)
  8. Tooth abscess (pus formation in tooth)
  9. Petit mal epilepsy (absence seizure)
  10. Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)

60+:

  1. Rash
  2. Diarrhoea
  3. Abdominal pain
  4. Back pain
  5. C-reactive protein increased
  6. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  7. Pyelonephritis (inflammation of kidney caused by bacteria)
  8. Neutropenia (an abnormally low number of neutrophils)
  9. Asthenia (weakness)
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

What are the existing conditions these people have? *

  1. Pain: 21 people, 26.58%
  2. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 15 people, 18.99%
  3. Febrile Bone Marrow Aplasia (bone marrow greatly decreases or stops production of blood cells): 15 people, 18.99%
  4. Multiple Myeloma (cancer of the plasma cells): 14 people, 17.72%
  5. Constipation: 14 people, 17.72%
  6. Hypokalemia (low potassium): 11 people, 13.92%
  7. Back Pain: 9 people, 11.39%
  8. Depression: 8 people, 10.13%
  9. Insomnia (sleeplessness): 8 people, 10.13%
  10. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 8 people, 10.13%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Amlodipine and Pentacarinat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amlodipine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pentacarinat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amlodipine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pentacarinat and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate and pentamidine isethionate (the active ingredients of Amlodipine and Pentacarinat, respectively), and Amlodipine and Pentacarinat (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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