Amphetamine sulfate and Adderall drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amphetamine sulfate (amphetamine sulfate) and Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate). Common drug interactions include pruritus among females.

The phase IV clinical study analyzes what interactions people have when they take Amphetamine sulfate and Adderall. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Amphetamine sulfate?

Amphetamine sulfate has active ingredients of amphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 687 Amphetamine sulfate users. Check the latest studies of Amphetamine sulfate.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,225 Adderall users. Check the latest studies of Adderall.



On Aug, 01, 2026

15 people who take Amphetamine sulfate and Adderall together, and have interactions are studied.

Amphetamine sulfate and Adderall drug interactions.

What are the common drug interactions of Amphetamine Sulfate and Adderall, by gender? *:

female:

  1. Pruritus (severe itching of the skin)
  2. Road traffic accident
  3. Sleep-related eating disorder (abnormal eating patterns during the night)
  4. Somnambulism (sleep walking)
  5. Surgery
  6. Pain in extremity
  7. Somnolence (a state of near-sleep, a strong desire for sleep)
  8. Weight decreased
  9. Allergy to metals
  10. Bladder spasm

male:

n/a

What are the common drug interactions of Amphetamine Sulfate and Adderall, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anxiety
  2. Back injury
  3. Craniocerebral injury (injury to cranium and brain)
  4. Hyperthyroidism (over activity of the thyroid gland)
  5. Neck pain
  6. Panic attack
  7. Pruritus (severe itching of the skin)
  8. Road traffic accident
  9. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  10. Sleep-related eating disorder (abnormal eating patterns during the night)

30-39:

  1. Heart rate decreased

40-49:

  1. Ear infection
  2. Hospitalisation
  3. Hot flush (sudden feelings of heat)
  4. Nasopharyngitis (inflammation of the nasopharynx)
  5. Nausea (feeling of having an urge to vomit)
  6. Pain in extremity
  7. Respiratory disorder (respiratory disease)
  8. Somnolence (a state of near-sleep, a strong desire for sleep)
  9. Upper-airway cough syndrome
  10. Urinary tract infection

50-59:

  1. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  2. Flushing (the warm, red condition of human skin)
  3. Intracranial aneurysm (bulging, weak area in the wall of a cranial artery)
  4. Loss of consciousness
  5. Neuropathy peripheral (surface nerve damage)
  6. Road traffic accident
  7. Somatic delusion (false belief that one's bodily functioning, sensation, or appearance is grossly abnormal)
  8. Somnolence (a state of near-sleep, a strong desire for sleep)

60+:

n/a

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 33.33%
  2. Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 4 people, 26.67%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 26.67%
  4. Drowsiness: 4 people, 26.67%
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 2 people, 13.33%
  6. Neuralgia (pain in one or more nerves): 2 people, 13.33%
  7. Visual Impairment: 1 person, 6.67%
  8. Hair Loss: 1 person, 6.67%
  9. Back Pain: 1 person, 6.67%
  10. Bipolar Ii Disorder (characterized by at least one episode of hypomania and at least one episode of major depression): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Amphetamine sulfate and Adderall:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amphetamine sulfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Adderall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amphetamine sulfate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adderall and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on amphetamine sulfate and amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate (the active ingredients of Amphetamine sulfate and Adderall, respectively), and Amphetamine sulfate and Adderall (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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