Amrix and Amoxicillin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amrix (cyclobenzaprine hydrochloride) and Amoxicillin (amoxicillin). Common drug interactions include intestinal obstruction among females and injury among males.

The phase IV clinical study analyzes what interactions people have when they take Amrix and Amoxicillin. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Amrix?

Amrix has active ingredients of cyclobenzaprine hydrochloride. It is often used in back pain. eHealthMe is studying from 1,130 Amrix users. Check the latest studies of Amrix.

What is Amoxicillin?

Amoxicillin has active ingredients of amoxicillin. It is often used in infection. eHealthMe is studying from 99,235 Amoxicillin users. Check the latest studies of Amoxicillin.



On Aug, 07, 2026

40 people who take Amrix and Amoxicillin together, and have interactions are studied.

Amrix and Amoxicillin drug interactions.

What are the common drug interactions of Amrix and Amoxicillin, by gender? *:

female:

  1. Intestinal obstruction
  2. Ovarian adhesion (bands of scar-like tissue that form between ovary and nearby organ)
  3. Pain
  4. Palpitations (feelings or sensations that your heart is pounding or racing)
  5. Pelvic adhesions
  6. Pelvic pain
  7. Salpingitis (an infection and inflammation in the fallopian tubes)
  8. Tricuspid valve incompetence (inefficient heart valve)
  9. Urinary tract infection
  10. Renal tubular necrosis (death of kidney tubules)

male:

  1. Injury
  2. Fall
  3. Fatigue (feeling of tiredness)
  4. Haematuria (presence of blood in urine)
  5. Pleural fibrosis (formation of fibrous tissue in lung)
  6. Rales (an abnormal respiratory sound characterized by fine crackles)
  7. Splenomegaly (enlargement of spleen)
  8. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  9. Balance disorder
  10. Bruxism (habitual grinding of the teeth, typically during sleep)

What are the common drug interactions of Amrix and Amoxicillin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Drug dependence

30-39:

  1. Anxiety
  2. Abdominal distension
  3. Haematuria (presence of blood in urine)
  4. Injury
  5. Pleural fibrosis (formation of fibrous tissue in lung)
  6. Rales (an abnormal respiratory sound characterized by fine crackles)
  7. Splenomegaly (enlargement of spleen)
  8. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  9. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  10. Cardiomegaly (increased size of heart than normal)

40-49:

  1. Arthralgia (joint pain)
  2. Incision site infection (infection at incision site)
  3. Migraine (headache)
  4. Surgery
  5. Urinary tract infection

50-59:

  1. Mitral valve incompetence (inefficient heart valve)
  2. Mood disorder due to a general medical condition
  3. Multiple injuries
  4. Obesity (having too much body fat)
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  6. Ovarian cyst (fluid filled sac of the ovary)
  7. Polycystic ovaries (cysts in the ovaries that occurs when the follicle stops developing)
  8. Procedural pain
  9. Renal impairment (severely reduced kidney function)
  10. Renal injury (kidney injury)

60+:

  1. Fall
  2. Balance disorder
  3. Somnolence (a state of near-sleep, a strong desire for sleep)
  4. Tooth extraction
  5. Toothache (tooth pain)
  6. Chronic kidney disease
  7. Renal tubular necrosis (death of kidney tubules)
  8. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  9. Blood cholesterol increased
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 20.00%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 20.00%
  3. Pain: 7 people, 17.50%
  4. High Blood Pressure: 6 people, 15.00%
  5. Hypersensitivity: 5 people, 12.50%
  6. Muscle Aches (muscle pain): 4 people, 10.00%
  7. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 10.00%
  8. Inflammation: 4 people, 10.00%
  9. Migraine (headache): 3 people, 7.50%
  10. Immunodeficiency Common Variable: 3 people, 7.50%

* Approximation only. Some reports may have incomplete information.

Do you take Amrix and Amoxicillin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Amrix and Amoxicillin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amrix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Amoxicillin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amrix and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amoxicillin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cyclobenzaprine hydrochloride and amoxicillin (the active ingredients of Amrix and Amoxicillin, respectively), and Amrix and Amoxicillin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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