Anusol hc and Simvastatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Anusol hc (hydrocortisone) and Simvastatin (simvastatin). Common drug interactions include tachycardia among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Anusol hc and Simvastatin. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Anusol hc?

Anusol hc has active ingredients of hydrocortisone. It is often used in hemorrhoids. eHealthMe is studying from 679 Anusol hc users. Check the latest studies of Anusol hc.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,967 Simvastatin users. Check the latest studies of Simvastatin.

On Apr, 24, 2026

23 people who take Anusol hc and Simvastatin together, and have interactions are studied.

Anusol hc and Simvastatin drug interactions.

What are the common drug interactions of Anusol Hc and Simvastatin, by gender? *:

female:

Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Urinary hesitation (difficulty in beginning the flow of urine)
Urinary tract infection
Diarrhoea
Abdominal distension
Abdominal pain
Angina pectoris (chest pain due to ischemia of the heart muscle)
Bradycardia (abnormally slow heart action)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Colitis ulcerative (inflammation of colon with ulcer)

male:

Diarrhoea
Drug ineffective
Bradycardia (abnormally slow heart action)
Cardiomegaly (increased size of heart than normal)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Disease progression
Drug dependence

What are the common drug interactions of Anusol Hc and Simvastatin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Renal failure acute (rapid kidney dysfunction)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Staphylococcal infection (an infection with staphylococcus bacteria)

40-49:

n/a

50-59:

Bradycardia (abnormally slow heart action)
Abdominal distension
Abdominal pain
Angina pectoris (chest pain due to ischemia of the heart muscle)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Colitis ulcerative (inflammation of colon with ulcer)
Cough
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Drug hypersensitivity

60+:

Diarrhoea
Nausea (feeling of having an urge to vomit)
Breast cancer
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Chest pain
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Decreased appetite
Disease progression
Dizziness
Drug ineffective

What are the existing conditions these people have? *

Pain: 5 people, 21.74%
Stress And Anxiety: 3 people, 13.04%
Stable Angina (a constant chest pain): 3 people, 13.04%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 13.04%
Thyroid Diseases: 2 people, 8.70%
Procedural Pain: 2 people, 8.70%
Osteoporosis (bones weak and more likely to break): 2 people, 8.70%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 2 people, 8.70%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 2 people, 8.70%
Haemorrhage (bleeding): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Anusol hc and Simvastatin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously