Aprepitant and Kytril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aprepitant (aprepitant) and Kytril (granisetron hydrochloride). Common drug interactions include pain among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Aprepitant and Kytril. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Aprepitant?

Aprepitant has active ingredients of aprepitant. eHealthMe is studying from 6,992 Aprepitant users. Check the latest studies of Aprepitant.

What is Kytril?

Kytril has active ingredients of granisetron hydrochloride. eHealthMe is studying from 10,766 Kytril users. Check the latest studies of Kytril.

On Jul, 26, 2026

33 people who take Aprepitant and Kytril together, and have interactions are studied.

Aprepitant and Kytril drug interactions.

What are the common drug interactions of Aprepitant and Kytril, by gender? *:

female:

Pain
Psychological trauma
Sensation of heaviness
Tinnitus (a ringing in the ears)
Tremor (trembling or shaking movements in one or more parts of your body)
Nausea (feeling of having an urge to vomit)
Headache (pain in head)
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)
Vertigo
Cerebral infarction (less blood supply to brain resulting tissue damage)

male:

Pneumonia
Bacterial translocation
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hyperglycaemia (high blood sugar)
Melaena (the passage of black, tarry stools)
Mucosal inflammation (infection of mucous membrane)
Nausea (feeling of having an urge to vomit)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Stomatitis (inflammation of mucous membrane of mouth)
Vomiting

What are the common drug interactions of Aprepitant and Kytril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Bacterial translocation
Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)
Neutropenic colitis (inflammation of the cecum, often with involvement of the ascending colon and ileum, a life threatening condition)

20-29:

n/a

30-39:

Eyelid ptosis (falling of the upper or lower eyelid)
Haemorrhage subcutaneous (bleeding from skin)
Headache (pain in head)
Iiird nerve paralysis (totally closed eyelid and a down and out deviation of the eye)
Mydriasis (a dilation of the pupil)
Nausea (feeling of having an urge to vomit)
Tinnitus (a ringing in the ears)

40-49:

Disseminated intravascular coagulation (systemic activation of blood coagulation)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hepatic failure (liver failure)
Hepatic necrosis (large portions of liver die off due to severe liver disease)
Hepatitis acute
Hepatitis cholestatic (flow of bile from the liver is slowed or blocked)
Hypotension (abnormally low blood pressure)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Thrombocytopenia (decrease of platelets in blood)
Alopecia (absence of hair from areas of the body)

50-59:

Nausea (feeling of having an urge to vomit)
Pericarditis malignant (cancerous inflammation of the pericardium)
Rectal haemorrhage (bleeding from anus)
Chest discomfort
Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Flushing (the warm, red condition of human skin)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)

60+:

Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)
Vertigo
Angina pectoris (chest pain due to ischemia of the heart muscle)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blindness
Blood calcium increased
Blood creatinine increased
Bone pain
Cerebral infarction (less blood supply to brain resulting tissue damage)
Chills (felling of cold)

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 6 people, 18.18%
Breast Cancer: 4 people, 12.12%
Back Pain: 3 people, 9.09%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 3 people, 9.09%
Respiratory Tract Infection: 2 people, 6.06%
Pulmonary Embolism (blockage of the main artery of the lung): 2 people, 6.06%
Prostate Cancer Metastatic: 2 people, 6.06%
Nausea And Vomiting: 2 people, 6.06%
Itching: 2 people, 6.06%
Hepatic Pain (pain in liver): 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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