Apresoline and Dexamethasone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Apresoline (hydralazine hydrochloride) and Dexamethasone (dexamethasone). Common drug interactions include asthma among females and osteonecrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Apresoline and Dexamethasone. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Apresoline?

Apresoline has active ingredients of hydralazine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 2,475 Apresoline users. Check the latest studies of Apresoline.

What is Dexamethasone?

Dexamethasone has active ingredients of dexamethasone. It is often used in multiple myeloma. eHealthMe is studying from 161,927 Dexamethasone users. Check the latest studies of Dexamethasone.



On Jul, 31, 2026

27 people who take Apresoline and Dexamethasone together, and have interactions are studied.

Apresoline and Dexamethasone drug interactions.

What are the common drug interactions of Apresoline and Dexamethasone, by gender? *:

female:

  1. Asthma
  2. Bacteraemia (presence of bacteria in the blood)
  3. Bone disorder
  4. Bone fragmentation
  5. Breast cancer recurrent
  6. Candidiasis (candidiasis or thrush is a fungal infection)
  7. Colitis (inflammation of colon)
  8. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  9. Costochondritis (chest wall pain)
  10. Decreased appetite

male:

  1. Osteonecrosis (death of bone)
  2. Premature labour
  3. Cerebral haemorrhage (bleeding within the brain)
  4. Coagulopathy (blood's ability to clot is impaired)
  5. Coma (state of unconsciousness lasting more than six hours)
  6. Confusional state
  7. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  8. Haematoma (collection of blood outside the blood vessels)
  9. Headache (pain in head)
  10. Heparin-induced thrombocytopenia

What are the common drug interactions of Apresoline and Dexamethasone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Anal fistula
  2. Hypokalaemia (low potassium)
  3. Pelvic infection
  4. Wound infection

50-59:

  1. Anaemia (lack of blood)
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Anisocytosis (patient's red blood cells are of unequal size)
  4. Anxiety
  5. Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
  6. Asthma
  7. Bacteraemia (presence of bacteria in the blood)
  8. Bedridden
  9. Blood glucose increased
  10. Bone disorder

60+:

  1. Nausea (feeling of having an urge to vomit)
  2. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  3. Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
  4. Asthma
  5. Bacteraemia (presence of bacteria in the blood)
  6. Bone disorder
  7. Bone fragmentation
  8. Breast cancer recurrent
  9. Candidiasis (candidiasis or thrush is a fungal infection)
  10. Colitis (inflammation of colon)

What are the existing conditions these people have? *

  1. Pain: 4 people, 14.81%
  2. Nausea (feeling of having an urge to vomit): 4 people, 14.81%
  3. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 4 people, 14.81%
  4. Stress And Anxiety: 3 people, 11.11%
  5. Ovarian Epithelial Cancer (cancer that begins in the cells on the surface of the ovary): 3 people, 11.11%
  6. Fever: 3 people, 11.11%
  7. Delirium (wild excitement): 3 people, 11.11%
  8. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 3 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Apresoline and Dexamethasone?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Apresoline and Dexamethasone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Apresoline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Dexamethasone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Apresoline and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dexamethasone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on hydralazine hydrochloride and dexamethasone (the active ingredients of Apresoline and Dexamethasone, respectively), and Apresoline and Dexamethasone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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