Arginine and Simvastatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Arginine (l - arginine) and Simvastatin (simvastatin). Common drug interactions include myalgia among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Arginine and Simvastatin. It is created by eHealthMe based on reports of 96 people who take the same drugs from the FDA, and is updated regularly.

What is Arginine?

Arginine has active ingredients of l - arginine. It is often used in erection problems. eHealthMe is studying from 2,612 Arginine users. Check the latest studies of Arginine.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,969 Simvastatin users. Check the latest studies of Simvastatin.

On Jul, 10, 2026

96 people who take Arginine and Simvastatin together, and have interactions are studied.

Arginine and Simvastatin drug interactions.

What are the common drug interactions of Arginine and Simvastatin, by gender? *:

female:

Myalgia (muscle pain)
Pain in extremity
Renal disorder (kidney disease)
Somnolence (a state of near-sleep, a strong desire for sleep)
Alopecia (absence of hair from areas of the body)
Death
General physical health deterioration (weak health status)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Labyrinthitis (inflammation of the labyrinth or inner ear)
Overdose

male:

Diarrhoea
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Prostate cancer
Weight decreased
Activated partial thromboplastin time prolonged
Alanine aminotransferase increased
Anion gap decreased
Anion gap increased
Aortic aneurysm rupture (enlarged aortic artery rapture caused by a weakening of the artery wall)
Base excess decreased

What are the common drug interactions of Arginine and Simvastatin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Pulmonary hypertension (increase in blood pressure in the lung artery)
Right ventricular failure (right half of the heart fails to work)

10-19:

n/a

20-29:

Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)

30-39:

n/a

40-49:

Hemiparesis (weakness on one side of the body)

50-59:

Diarrhoea
Drug ineffective
Drug level below therapeutic
Erythema (redness of the skin)
Flushing (the warm, red condition of human skin)
Headache (pain in head)
Hypertransaminasaemia
Hypotension (abnormally low blood pressure)
Impaired work ability
Injection site pain

60+:

Asthenia (weakness)
Gait disturbance
Pain in extremity
Renal disorder (kidney disease)
Somnolence (a state of near-sleep, a strong desire for sleep)
Abdominal pain upper
Anaemia (lack of blood)
Arthralgia (joint pain)
Chronic kidney disease
Epistaxis (bleed from the nose)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 13.54%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 13 people, 13.54%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 7.29%
Multiple Myeloma (cancer of the plasma cells): 6 people, 6.25%
Cardiac Disorder: 6 people, 6.25%
Type 2 Diabetes: 5 people, 5.21%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 5.21%
Depression: 5 people, 5.21%
Allergic Granulomatous Angiitis (allergic inflammation of a blood vessel or lymph duct): 5 people, 5.21%

* Approximation only. Some reports may have incomplete information.

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