Arginine and Zoloft drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Arginine (l - arginine) and Zoloft (sertraline hydrochloride). Common drug interactions include dehydration among females and hereditary angioedema among males.

The phase IV clinical study analyzes what interactions people have when they take Arginine and Zoloft. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Arginine?

Arginine has active ingredients of l - arginine. It is often used in erection problems. eHealthMe is studying from 2,612 Arginine users. Check the latest studies of Arginine.

What is Zoloft?

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,798 Zoloft users. Check the latest studies of Zoloft.

On Jul, 26, 2026

25 people who take Arginine and Zoloft together, and have interactions are studied.

What are the common drug interactions of Arginine and Zoloft, by gender? *:

female:

Dehydration (dryness resulting from the removal of water)
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthma
Blood pressure decreased
Chest pain
Drug ineffective
Pericardial neoplasm (pericardial tumour)
Aggression
Chronic fatigue syndrome (disorder that causes extreme fatigue)

male:

Hereditary angioedema (recurrent episodes of severe swelling)
Infection
Hyperhidrosis (abnormally increased sweating)
Hypoaesthesia (reduced sense of touch or sensation)
Hypotension (abnormally low blood pressure)
Influenza
Oedema (fluid collection in tissue)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Respiratory rate decreased (less breathing rate/min)
Sedation

What are the common drug interactions of Arginine and Zoloft, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Aggression
Dysmenorrhoea (painful menstruation)
Hyperammonaemia
Mania (a state of abnormally elevated or irritable mood)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Sepsis (a severe blood infection that can lead to organ failure and death)
Sinusitis (inflammation of sinus)
Vomiting

20-29:

Drug ineffective
Dyspnoea (difficult or laboured respiration)
Insomnia (sleeplessness)
Pain
Pain in extremity
Renal pain (kidney pain)

30-39:

Drug ineffective

40-49:

n/a

50-59:

Infection
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Upper respiratory tract infection
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthma
Blood pressure decreased
Chest pain
Influenza
Pericardial neoplasm (pericardial tumour)

60+:

Chronic fatigue syndrome (disorder that causes extreme fatigue)
Chronic kidney disease
Fibromyalgia (a long-term condition which causes pain all over the body)
Hypersensitivity
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Septic shock (shock due to blood infection)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 8 people, 32.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 20.00%
Immune System Disorder: 4 people, 16.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 16.00%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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