Arimidex and Topamax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Arimidex (anastrozole) and Topamax (topiramate). Common drug interactions include osteoporosis among females and insomnia among males.

The phase IV clinical study analyzes what interactions people have when they take Arimidex and Topamax. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Arimidex?

Arimidex has active ingredients of anastrozole. It is often used in breast cancer. eHealthMe is studying from 22,642 Arimidex users. Check the latest studies of Arimidex.

What is Topamax?

Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 58,954 Topamax users. Check the latest studies of Topamax.



On Jul, 13, 2026

59 people who take Arimidex and Topamax together, and have interactions are studied.

Arimidex and Topamax drug interactions.

What are the common drug interactions of Arimidex and Topamax, by gender? *:

female:

  1. Osteoporosis (bones weak and more likely to break)
  2. Weight increased
  3. Vomiting
  4. Arterial haemorrhage
  5. Delirium (wild excitement)
  6. Dizziness
  7. Fluid imbalance (imbalance of fluid in body in intake and fluid lost)
  8. Hypertension (high blood pressure)
  9. Loss of consciousness
  10. Pancreatic disorder

male:

  1. Insomnia (sleeplessness)
  2. Impaired healing

What are the common drug interactions of Arimidex and Topamax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Neoplasm malignant (cancer tumour)
  2. Pain in extremity
  3. Upper limb fracture
  4. Abdominal pain upper
  5. Cholecystitis chronic (long lasting infection of gallbladder)
  6. Decreased appetite
  7. Device related infection
  8. Fall
  9. Gallbladder cholesterolosis (accumulation and deposition of cholesterol inside of the)
  10. Malaise (a feeling of general discomfort or uneasiness)

30-39:

  1. Pain
  2. Abscess (pus)
  3. Anxiety
  4. Bone disorder
  5. Deformity (disfigurement)
  6. Discomfort
  7. Eating disorder symptom
  8. Emotional distress
  9. Facial pain
  10. Impaired healing

40-49:

  1. Malignant melanoma (skin cancer rises from melancytes)
  2. Alopecia (absence of hair from areas of the body)
  3. Arthralgia (joint pain)
  4. Blood sodium decreased
  5. Head injury
  6. Irritable bowel syndrome
  7. Maternal exposure during pregnancy (use of substance during pregnancy)
  8. Muscle spasms (muscle contraction)
  9. Nightmare (unpleasant dream)
  10. Pain

50-59:

  1. Abnormal dreams
  2. Agitation (state of anxiety or nervous excitement)
  3. Anaemia (lack of blood)
  4. Anal inflammation
  5. Anger
  6. Arterial haemorrhage
  7. Blood cholesterol increased
  8. Blood glucose decreased
  9. Blood lactate dehydrogenase increased
  10. Blood magnesium decreased

60+:

  1. Arthralgia (joint pain)
  2. Bone disorder
  3. Bone pain
  4. Burning sensation
  5. Cardiac disorder
  6. Cerebral haemorrhage (bleeding within the brain)
  7. Cough
  8. Dysgeusia (disorder of the sense of taste)
  9. Dysphonia (speech disorder attributable to a disorder of phonation)
  10. Excoriation (to tear or wear off the skin of)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 22.03%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 12 people, 20.34%
  3. High Blood Cholesterol: 5 people, 8.47%
  4. Fluid Imbalance (imbalance of fluid in body in intake and fluid lost): 5 people, 8.47%
  5. High Blood Pressure: 4 people, 6.78%
  6. Pain: 3 people, 5.08%
  7. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 5.08%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 5.08%
  9. Breast Cancer Metastatic: 3 people, 5.08%
  10. Breast Cancer Female: 3 people, 5.08%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Arimidex and Topamax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Arimidex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Topamax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Arimidex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Topamax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on anastrozole and topiramate (the active ingredients of Arimidex and Topamax, respectively), and Arimidex and Topamax (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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